Results 121 to 130 of about 66,315 (318)

Phase Separation Studies of Complexes of Intrinsically Disordered Protein Tau and Anionic Liposomes [PDF]

open access: bronze, 2020
Christine Tchounwou   +5 more
openalex   +1 more source

Deciphering the 'fuzzy' interaction of FG nucleoporins and transport factors using SANS

open access: yes, 2018
The largely intrinsically disordered phenylalanine-glycine-rich nucleoporins (FG Nups) underline a selectivity mechanism, which enables the rapid translocation of transport factors (TFs) through the nuclear pore complexes (NPCs).
Cowburn, David   +3 more
core   +1 more source

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

open access: yesAdvanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo   +4 more
wiley   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

open access: yesAdvanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu   +14 more
wiley   +1 more source

CHARMM36m: An improved force field for folded and intrinsically disordered proteins.

open access: yes, 2016
The all-atom additive CHARMM36 protein force field is widely used in molecular modeling and simulations. We present its refinement, CHARMM36m (http://mackerell.umaryland.edu/charmm_ff.shtml), with improved accuracy in generating polypeptide backbone ...
de Groot, B.   +7 more
core   +1 more source

The Prediction of Intrinsically Disordered Proteins Based on Feature Selection

open access: yesAlgorithms, 2019
Intrinsically disordered proteins perform a variety of important biological functions, which makes their accurate prediction useful for a wide range of applications.
Hao He, Jiaxiang Zhao, Guiling Sun
doaj   +1 more source

Smarter Sensors Through Machine Learning: Historical Insights and Emerging Trends across Sensor Technologies

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights how machine learning (ML) algorithms are employed to enhance sensor performance, focusing on gas and physical sensors such as haptic and strain devices. By addressing current bottlenecks and enabling simultaneous improvement of multiple metrics, these approaches pave the way toward next‐generation, real‐world sensor applications.
Kichul Lee   +17 more
wiley   +1 more source

Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing

open access: yesNature Communications, 2018
Many proteins which sense membrane curvature contain intrinsically disordered domains. Here the authors use Monte Carlo simulations combined with experimental approaches and report that disordered domains are potent sensors of membrane curvature.
Wade F. Zeno   +7 more
doaj   +1 more source

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