Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
Advanced Functional Materials, EarlyView.FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source
How Robust Is the Mechanism of Folding-Upon-Binding for an Intrinsically Disordered Protein? [PDF]
, 2018 Daniela Bonetti +4 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava +7 more
wiley +1 more source
Disorder-to-Order Transition in the CyaA Toxin RTX Domain: Implications for Toxin Secretion
Toxins, 2014 The past decade has seen a fundamental reappraisal of the protein structure-to-function paradigm because it became evident that a significant fraction of polypeptides are lacking ordered structures under physiological conditions.
Ana-Cristina Sotomayor-Pérez +2 more
doaj +1 more source
Reviewer #1 (Public Review): Intrinsic protein disorder is insufficient to drive subnuclear clustering in embryonic transcription factors [PDF]
, 2023 Hannon Colleen E., Eisen Michael B.
openalex +1 more source
Advanced Functional Materials, EarlyView.Liquid crystalline inverted lipid phases and reverse micelles are self‐assembled lipid nanostructures that enhance the solubility, stability, and delivery of diverse therapeutics. This review integrates their physicochemical principles, formulation strategies, drug loading mechanisms, and biomedical applications, highlighting their growing ...
Numan Eczacioglu +3 more
wiley +1 more source
Distribution of Charged Residues Affects the Average Size and Shape of Intrinsically Disordered Proteins [PDF]
, 2022 Greta Bianchi +6 more
openalex +1 more source
Proteins, Processing, and Properties of Adhesive Fluid Condensates Purified from Mussels
Advanced Functional Materials, EarlyView.Mussels exhibit an unmatched proficiency for adhering to wet surfaces in salty environments—a remarkable ability that could inspire new biomedical and technical glues. The fluid protein condensates used to form the underwater mussel glue are extracted, reconstituted and characterized with advanced spectroscopy and nanomechanical analysis, revealing ...
Mathieu D. Rivard +8 more
wiley +1 more source
Low-resolution description of the conformational space for intrinsically disordered proteins [PDF]
, 2022 Georg Daniel Förster +5 more
openalex +3 more sources
Biological Functions of the Intrinsically Disordered N-Terminal Domain of the Prion Protein: A Possible Role of Liquid–Liquid Phase Separation [PDF]
, 2021 Stella A. Polido +2 more
openalex +1 more source