A Curated Rotamer Library for Common Post-Translational Modifications of Proteins [PDF]
Sidechain rotamer libraries of the common amino acids of a protein are useful for folded protein structure determination and for generating ensembles of intrinsically disordered proteins (IDPs). However much of protein function is modulated beyond the translated sequence through thFiguree introduction of post-translational modifications (PTMs). In this
arxiv
Intrinsically disordered proteins in cellular signalling and regulation
Peter E. Wright, H. Dyson
semanticscholar +1 more source
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi+4 more
wiley +1 more source
Diffusion of intrinsically disordered proteins within viscoelastic membraneless droplets [PDF]
In living cells, intrinsically disordered proteins (IDPs), such as FUS and DDX4, undergo phase separation, forming biomolecular condensates. Using molecular dynamics simulations, we investigate their behavior in their respective homogenous droplets. We find that the proteins exhibit transient subdiffusion due to the viscoelastic nature and confinement ...
arxiv
Multiple Nucleic Acid Binding Sites and Intrinsic Disorder of Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein: Implications for Ribonucleocapsid Protein Packaging [PDF]
Chung‐ke Chang+7 more
openalex +1 more source
This review examines the critical role of neighboring active motifs in heterogeneous catalysts, emphasizing how their synergistic cooperativity can be rationally designed to modulate catalytic properties. The discussion centers on the modulation of electronic and geometric structures, categorizing the catalytic systems into metal‐acid (Brønsted/Lewis ...
Peng Yuan+2 more
wiley +1 more source
Abundance of intrinsic disorder in SV-IV, a multifunctional androgen-dependent protein secreted from rat seminal vesicle [PDF]
Silvia Vilasi, Raffaele Ragone
openalex +1 more source
Photothermal neuromodulation is a promising technique for versatile neural signal study and treatment development. To further develop these technologies and optimize their effectiveness, transparent electrical temperature sensors with high thermal sensitivity and resolution are essential for accurately monitoring temperature changes during ...
Jee Woong Lee+7 more
wiley +1 more source
Electrostatics and hydrophobicity in the dynamics of intrinsically disordered proteins. [PDF]
Vancraenenbroeck R, Hofmann H.
europepmc +1 more source
Large-Scale Analysis of Thermostable, Mammalian Proteins Provides Insights into the Intrinsically Disordered Proteome [PDF]
Charles A. Galea+10 more
openalex +1 more source