Results 91 to 100 of about 727,311 (310)

The mammal fauna of Italy: a review

Hystrix, the Italian Journal of Mammalogy, 1996
<strong>Abstract</strong> A synthesis on the status of the Italian mammals species is reported. For each order, faunistic and biogeographic data and conservation concern are considered.
Giovanni Amori, Francesco Maria Angelici, Claudio Prigioni, Augusto Vigna Taglianti   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Genetic monitoring detects an overlooked cryptic species and reveals the diversity and distribution of three invasive Rattus congeners in South Africa [PDF]

, 2011
Background: South Africa's long and extensive trade activity has ensured ample opportunities for exotic species introduction. Whereas the rich biodiversity of endemic southern African fauna has been the focus of many studies, invasive vertebrates are ...
Jennifer M Lamb, von Maltitz Emil, van Hooft, W.F., Deenadayalan Nair, Chimimba, C.T., Taylor Peter J, van Hooft, Pim, Lamb3, Jennifer M., Mostert, Elmarie, Downs Sarah, Christian T Chimimba, Kirsten, F., Contrafatto Giancarlo, Brettschneider, Helene, Emil von Maltitz, Giancarlo Contrafatto, Downs, Sarah, Steven R Belmain, Brettschneider, H., Chimimba, Christian Timothy, Sarah Downs, Bastos Armanda D, Nair, Deenadayalan, Helene Brettschneider, Belmain, Steven R., Contrafatto, Giancarlo, Nair Deenadayalan, Contrafatto, G., Lamb Jennifer M, Lamb, J.M., Taylor, Peter J., Lamb, Jennifer M., Maltitz, E., Nair, D., Kirsten, Frikkie, Elmarie Mostert, Peter J Taylor, van Hooft Pim, Chimimba, Christian T., Bastos, Armanda D., Kirsten Frikkie, Downs, S., Taylor, P.J., Taylor, P.J. (Peter John), von Maltitz, Emil, Belmain Steven R, Armanda D Bastos, Mostert, E., Bastos, Armanda D.S., Pim van Hooft, Hooft, W.F., van, Chimimba Christian T, Bastos, A.D.S., Frikkie Kirsten, Mostert Elmarie, Brettschneider Helene, Belmain, S.R., Maltitz, Emil von   +57 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Rahui And Marine Construction: Potential For Enhancement of Taonga species [PDF]

, 2010
The aims of my study were to investigate whether marine reserves enhance intertidal species used by Māori in a traditional or contemporary sense, and whether artificial structures in the intertidal region (such as wharf and bridge pilings) provide ...
Fox, Danielle
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

On the risk of extinction of a wild plant species through spillover of a biological control agent: analysis of an ecosystem compartment model [PDF]

, 2008
Invasive plant species can be controlled by introducing one or more of their natural enemies (herbivores) from their native range; however such introduction entails the risk that the introduced natural enemy will attack indigenous plant species in the ...
Hemerik, L., Ierland, E.C., van, Werf, W., van der, Chalak-Haghighi, M.   +3 more
core  

Reassessment of the invasion history of two species of Cakile (Brassicaceae) in Australia [PDF]

, 2013
In this paper we revisit the invasion history of two species of Cakile in Australia. Cakile edentula subsp. edentula arrived in the mid 19th Century and spread into coastal strandline habitat from the southeast towards the west and to the north; Cakile ...
Mesgaran, Mohsen B., Ohadi, Sara, Ades, Peter K., Cousens, Roger D.   +3 more
core   +1 more source

Who pollinates exotic plants? A global assessment across native and exotic ranges

Global Ecology and Conservation
The spread of exotic plant species is a global issue with substantial ecological and economic costs. One factor that can contribute to their capacity to establish and spread beyond their native range is their ability to attract novel pollinators (i.e ...
Natthaphong Chitchak, Piriya Hassa, Paweena Traiperm, Alyssa B. Stewart   +3 more
doaj   +1 more source