Results 91 to 100 of about 9,035,172 (245)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Influence of different nature cardiotonic medicines on the cytokine system of failing myocardium atthe pressure overload conditions in experimental animals

Кубанский научный медицинский вестник, 2015
In the work the efficacy of influence of cardiotonic drugs on the cytokine system changes in the response to acute maximal myocardial pressure overload in congestive heart failure (HF) animals was study in controlled randomized trial.
D. I. Ionov, M. M. Fedorova, P. A. Galenko-Yaroshevsky, G. V. Sukoyan, N. V. Gongadze   +4 more
doaj  

Introduction to odontoid fractures: controversies in the management of odontoid fractures [PDF]

, 2000
Gregory J. Przybylski
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Efficacy of different cardiotonic drug on severity of endotoxemia under heart failure coupled with systemic inflammatory syndrome in experiments

Кубанский научный медицинский вестник, 2015
On the model of systemic inflammatory response syndrome caused by toxi-allergic myocarditis 10-day duration in rabbits the efficacy of 5 days (beginning after 5 days from the injection of staphylococcus toxins) administration of the various ...
D. I. Ionov, M. M. Fedorova, G. V. Sukoyan, P. A. Galenko-Yaroshevsky, N. V. Gongadze   +4 more
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Errors in Introduction and Discussion [PDF]

, 2021

openalex   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

LiZn/LiAlO2/Li2O‐Derived Chemical Confinement Enabling Hierarchical and Oriented Li Plating/Stripping

Carbon Energy
ZnO with good lithiophilicity has widely been employed to modify the lithiophobic substrates and facilitate uniform lithium (Li) deposition. The overpotential of ZnO‐derived Li anode during cycling depends on the lithiophilicity of both LiZn and Li2O ...
Huaming Qian, Xifei Li, Qinchuan Chen, Jingjing Wang, Xiaohua Pu, Wei Xiao, Yanyan Cao, Mengxin Bai, Wenbin Li, Zhengdong Ma, Guiqiang Cao, Ruixian Duan, Gaini Zhang, Kaihua Xu, Kun Zhang, Wei Yan, Jiujun Zhang   +16 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source