Results 321 to 330 of about 483,569 (386)
Comprehensive functional splicing analysis of non-canonical CNGB3 variants using in vitro minigene splice assays. [PDF]
Rawnsley K+3 more
europepmc +1 more source
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng+4 more
wiley +1 more source
De Novo Genome Assembly and Annotation of the Arunachali Yak. [PDF]
Pukhrambam M+13 more
europepmc +1 more source
This study built a Wenchang chicken haplotype genome and integrated it with 29 others to create a chicken pangenome atlas. Analysis of 354 chickens revealed 185,205 structural variations (SVs), with one‐third derived from homology‐based and transposable elements.
Lihong Gu+9 more
wiley +1 more source
Pre-mRNA Splicing Functions in Plant Sexual Reproduction Development. [PDF]
Shao D, Gao X, Wei Y.
europepmc +1 more source
PMAT2: An efficient graphical assembly toolkit for comprehensive organellar genomes
We developed PMAT2, an advanced toolkit for lineage‐specific de novo assembly of plant, animal, and fungal mitochondrial genomes, as well as plant chloroplast genome. PMAT2 leverages optimized graph‐based strategies tailored to organelle genome complexity, enabling complete and accurate assemblies, even with approximately 1 × highly accurate PacBio ...
Fuchuan Han+10 more
wiley +1 more source
CpG methylation changes associated with hyperglycemia in type 1 diabetes occur at angiogenic glomerular and retinal gene loci. [PDF]
Shao X+12 more
europepmc +1 more source
New insights into applications of base editor in hereditary disorders
Abstract Hereditary disorders are a group of diseases caused by genetic mutations or chromosomal variations. Although the incidence of each genetic disorder is relatively low, patients affected by the disease generally experience a range of severe symptoms, including blindness, disability, and even premature death. In addition, the available treatments
Maoping Cai+8 more
wiley +1 more source
Mendelian randomization analysis reveals causal relationship between allergic diseases and influenza. [PDF]
Li H, Zong Y, He L, Sun Y, Shi W, Guo J.
europepmc +1 more source