Results 201 to 210 of about 209,653 (293)

Transcriptional readthrough precedes alternative splicing programs triggered in CML cells by imatinib. [PDF]

Sci Adv
Podszywałow-Bartnicka P, Shine M, Lin J, Neugebauer KM.   +3 more
europepmc   +1 more source

Reduced Cas9 transgene silencing by incorporation of intron sequences. [PDF]

Nat Commun
Arana S, Du PP, Vaughan-Jackson A, Enright N, Spees K, Valbuena R, Garcia CA, Nguyen T, Venida A, Seczynska M, Bintu L, Lehner PJ, Prolo LM, Bassik MC.   +13 more
europepmc   +1 more source

INTS1 is required for maintaining accurate transcriptional integrity and behavior in zebrafish. [PDF]

NAR Genom Bioinform
Confino S, Wexler Y, Fishman L, Gothilf Y, Rabani M.   +4 more
europepmc   +1 more source

Polygenic risk score and prostate specific antigen predict death from prostate cancer in men with intermediate aggressive cancer

International Journal of Cancer, EarlyView.
What's New? Using 21 SNPs, two novel PRS were constructed and used to develop two new machine‐learning classifiers, one for the detection of prostate cancer and the other for the prediction of its aggressiveness and subsequent mortality. The classifier for disease detection is built using the PRS as the sole feature, whereas the one for disease ...
Leandro Rodrigues Santiago, Efthymios Ladoukakis, Dorota Scibior‐Bentkowska, Belinda Nedjai   +3 more
wiley   +1 more source

Comprehensive analysis of the role of ASC1 and APE2 introns on cellular fitness, transcription, and post-transcriptional dynamics. [PDF]

FEBS J
Fidler E, Khan Z, Awada A, Dwyer K, Pangeni S, Sakamoto T, Ansari A.   +6 more
europepmc   +1 more source

Improving genetic diagnosis of hereditary tumor syndromes: From expanded gene panels to functional genomics

International Journal of Cancer, EarlyView.
Abstract Genetic tumor risk syndromes (genturis) contribute substantially to the overall cancer burden and provide opportunities for early detection, prevention, and individualized treatment. Yet, many affected individuals remain undiagnosed due to restrictive testing criteria and challenges in variant interpretation.
Mayra Sauer, Morghan C. Lucas, Vitus Prokosch, Thomas Keßler, Thomas Risch, Andreas Laner, Jan Henkel, Anna Benet‐Pagès, Ariane Hallermayr, Verena Steinke‐Lange, Elke Holinski‐Feder, Barbara Klink   +11 more
wiley   +1 more source

Intron [PDF]

, 2018
openaire   +1 more source

The complete mitochondrial genome sequence of the angel-wing mushroom <i>Pleurocybella porrigens</i>. [PDF]

Mitochondrial DNA B Resour
Mitsukuni K, Watanabe N, Sekimata K, Zhang J, Ono A, Tanaka Y, Suzuki T.   +6 more
europepmc   +1 more source

Antiviral regulator TRIM25 as a prognostic marker of better survival in Merkel cell carcinoma: Association with MCPyV status

International Journal of Cancer, EarlyView.
What's New? TRIM25 is known for its role in antiviral immunity and association with poor prognosis in various cancers. This study reveals an association between high TRIM25 expression and Merkel cell polyomavirus positivity in Merkel cell carcinoma.
Klaus W. Fagerstedt, Sami Kilpinen, Johanna Arola, Benjamin Z. Sundqvist, Tom Böhling, Leif C. Andersson, Harri Sihto   +6 more
wiley   +1 more source

Omics-based dissection of alternative splicing and the regulatory architecture in fungal genomes. [PDF]

Curr Res Microb Sci
Neves-da-Rocha J, Lopes MER, Santos-Saboya MJ, Azevedo MIG, Petrucelli MF, Rossi A, Martinez-Rossi NM.   +6 more
europepmc   +1 more source