Results 211 to 220 of about 222,325 (351)

Co‐Opting MBNL‐Dependent Alternative Splicing Cassette Exons to Control Gene Therapy in Myotonic Dystrophy

open access: yesAnnals of Neurology, EarlyView.
Objective Myotonic dystrophy type 1 (DM1) is a highly variable, multisystemic genetic disorder caused by a CTG repeat expansion in the 3′ untranslated region of DMPK. Toxicity is exerted by repeat‐containing DMPK transcripts that sequester muscleblind‐like (MBNL) proteins and lead to deleterious yet predictable changes in alternative splicing.
Samuel T. Carrell   +3 more
wiley   +1 more source

Propagation of [D1,2]-type spliceosomal twin introns (stwintrons) in <i>Hypoxylaceae</i> and <i>Xylariaceae</i> fungi. [PDF]

open access: yesMicrobiol Spectr
Fekete E   +7 more
europepmc   +1 more source

The knock-in atlas: a web resource for targeted protein trap by CRISPR/Cas9 in human and mouse cell lines. [PDF]

open access: yesNucleic Acids Res
Hanai Y   +10 more
europepmc   +1 more source

Group II intron self-splicing. Alternative reaction conditions yield novel products.

open access: hybrid, 1988
Kevin A. Jarrell   +4 more
openalex   +1 more source

Unterschiedliche Reaktionen und Enzyme in der Psilocybin‐ Biosynthese bei Inocybe‐ und Psilocybe‐Pilzen

open access: yesAngewandte Chemie, EarlyView.
Pilze haben zweimal unabhängig gelernt, Psilocybin, den ikonischen Naturstoff der Zauberpilze, herzustellen. Dieser Artikel stellt die Enzyme des zweiten Biosyntheseweges vor, der in einem Risspilz gefunden wurde. Verblüffenderweise stimmen die beiden Wege in keiner Reaktion überein.
Tim Schäfer   +3 more
wiley   +1 more source

Intron turnover of slc26a1 and slc26a2 and convergence of intron insertion sites. [PDF]

open access: yesSci Rep
Torii K   +5 more
europepmc   +1 more source

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