Results 231 to 240 of about 137,846 (269)

De Novo Genome Sequence Assembly of the RNAi-Tractable Paramecium bursaria 186b: An Endosymbiotic Model System. [PDF]

Genome Biol Evol
Leonard G, Jenkins BH, Savory FR, Kilias ES, Maguire F, Milner DS, Richards TA.   +6 more
europepmc   +1 more source

Circular RNAs: Epigenetic Puppeteers Pulling the Strings of Cancer Pathogenesis

Medicine Bulletin, EarlyView.
ABSTRACT Circular RNAs (circRNAs), a unique class of endogenous noncoding RNAs characterized by their covalently closed loop structure, have emerged as pivotal players in cancer biology due to their exceptional stability, tissue‐specific expression, and diverse regulatory functions.
Yimao Wu, Zichang Chen, Junying Lee, Gokhan Zengin, Meng‐Yao Li   +4 more
wiley   +1 more source

Plant mitochondrial PORR proteins facilitate group II intron splicing by binding to distinct regions within their target introns. [PDF]

Nucleic Acids Res
Wang C, Quadrado M, Ngom T, Mireau H.
europepmc   +1 more source

New Technologies Empower Hemophilic Arthropathy Treatment: Focusing on Regenerative Medicine, Molecular Targeting, and Gene Therapy

Medicine Bulletin, EarlyView.
ABSTRACT Hemophilic arthropathy (HA), a major complication of hemophilia, is a chronic osteoarthropathy driven by repeated joint bleeding. Although traditional therapies such as coagulation factor replacement, physical rehabilitation, and surgery can manage symptoms, they cannot fundamentally repair established joint damage or break the pathological ...
Lin Sun, Yingnan Wang, Leyuan Zhao, Liqiang Lu, Fushan Hou, Chuan Yin, Kun Zhang, Yongqiang Hao, Jingke Fu   +8 more
wiley   +1 more source

Motor and Cognitive Outcome After Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson's Disease Harboring GBA1 Variant

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Deep brain stimulation (DBS) is effective for Parkinson's disease (PD); however, its efficacy varies with genetic background, such as the GBA1 variant—the causative gene of Gaucher disease—associated with increased PD risk and cognitive decline after subthalamic nucleus (STN)‐DBS.
Hikaru Kamo, Genko Oyama, Mai Shimizu, Haruka Takeshige‐Amano, Takashi Ogawa, Wataru Sako, Noriko Nishikawa, Taku Hatano, Yuanzhe Li, Hiroyo Yoshino, Manabu Funayama, Masanobu Ito, Hirokazu Iwamuro, Atsushi Umemura, Nobutaka Hattori   +14 more
wiley   +1 more source

Evolutionary dynamics and transcriptional diversification of GAD gene family in plants: a pan-species perspective in silico analysis. [PDF]

BMC Plant Biol
Niu Y, He Z, Yang X, Niu S.
europepmc   +1 more source

Integrating Long‐Read Nanopore Sequencing for Precision Resolution of Genomic Variants in Dystonia

Movement Disorders, EarlyView.
Abstract Background Although many individuals with dystonia present with features indicative of single‐gene etiologies, obtaining definitive genetic diagnoses can be challenging. Objective We assessed the value of nanopore‐based long‐read sequencing (LRS) in achieving molecular clarification of dystonic syndromes.
Ugo Sorrentino, Martin Pavlov, Nazanin Mirza‐Schreiber, Melanie Brugger, Theresa Brunet, Eugenia Tsoma, Alice Saparov, Ivana Dzinovic, Philip Harrer, Antonia M. Stehr, Matias Wagner, Erik Tilch, Barbara Wallacher, Shiraz Alhasan, Anne Koy, Alessio Di Fonzo, Miriam Kolnikova, Katarina Kusikova, Petra Havrankova, Raushana Tautanova, Sandy Lösecke, Sebastian Eck, Sylvia Boesch, Jan Necpal, Matej Skorvanek, Robert Jech, Holger Prokisch, Juliane Winkelmann, Konrad Oexle, Elisabeth Graf, Michael Zech   +30 more
wiley   +1 more source

Analysis of Intron 1 Inversion at F8 Gene in Severe Hemophilia A Patients by Inverse Shifting-PCR Referred from Isfahan Seyedolshohada Hospital

, 2013
Narges Roozafzay, Leila Kokabee, Sirous Zeinali, Morteza Karimipoor   +3 more
openalex   +1 more source

Genome-wide identification of AAAP gene family and expression analysis under abiotic stresses in Avena sativa. [PDF]

BMC Genomics
Ling L, Wang S, Zhang H, Yang F, Qu L.
europepmc   +1 more source

PPR596 Is Required for nad2 mRNA Splicing and Complex I Biogenesis in Mitochondria of Arabidopsis thaliana. [PDF]

Physiol Plant
Peters L, Wagner VC, Schoeller T, Dwiani S, Schallenberg-Rüdinger M, Meyer EH, Kühn K.   +6 more
europepmc   +1 more source