Results 281 to 290 of about 213,484 (340)
ERH regulates type II interferon immune signaling through post-transcriptional regulation of JAK2 mRNA. [PDF]
Soderholm A+13 more
europepmc +1 more source
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons+17 more
wiley +1 more source
Characteristics and Expression Profiles of Identified <i>WRKY</i> Genes in Barley Landraces Under Cold Stress. [PDF]
Zhou Y+6 more
europepmc +1 more source
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk+4 more
wiley +1 more source
Classification and Quantification of Unproductive Splicing Events. [PDF]
Zavileyskiy LG+3 more
europepmc +1 more source
Evolutionary dynamics of the calcium/cation antiporter superfamily in Brassicaceae: codon usage, selection pressure, and <i>BnCaCAs</i> role in abiotic stress response. [PDF]
Abedi A+4 more
europepmc +1 more source
Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola+3 more
wiley +1 more source
Exploring the Potential and Advancements of Circular RNA Therapeutics
Given the remarkable advantages in terms of stability, sustained expression profile, safety, wide range of druggable targets, scalable and cost‐effective manufacturing capabilities, circRNA is currently undergoing intensive investigation for various therapeutic applications such as vaccines, protein replacement, genetic disease treatment, gene therapy,
Lei Wang+6 more
wiley +1 more source