Results 311 to 320 of about 213,484 (340)
Some of the next articles are maybe not open access.
Origin of introns by ‘intronization’ of exonic sequences
Trends in Genetics, 2008The mechanisms of spliceosomal intron creation have proved elusive. Here we describe a new mechanism: the recruitment of internal exonic sequences ('intronization') in Caenorhabditis species. The numbers of intronization events and introns gained by other mechanisms are similar, suggesting that intronization significantly contributes to recent intron ...
Irimia, Manuel +5 more
openaire +4 more sources
Frühe Introns – späte Introns?
Biologie in unserer Zeit, 1995AbstractIntrons nennt man Nucleinsäuresequenzen, die mitten in Genregionen eingefügt sind, letztlich aber nicht in Polypeptidsequenzen übersetzt werden. Auch Prokaryoten und sogar Viren können unterbrochene Gene besitzen, aber nur bei den Eukaryoten findet man die „klassischen”︁ Introns, die dort fast alle Strukturgene zerstückeln.
openaire +2 more sources
Blood, 2013
In this issue of Blood, Yuan et al provide evidence that processing of the first intronic sequence within the von Willebrand factor (vWF) gene facilitates expression by endothelial cells regardless of the source of the intron, while intron processing is irrelevant for vWF expression by megakaryocytes.(1)
openaire +3 more sources
In this issue of Blood, Yuan et al provide evidence that processing of the first intronic sequence within the von Willebrand factor (vWF) gene facilitates expression by endothelial cells regardless of the source of the intron, while intron processing is irrelevant for vWF expression by megakaryocytes.(1)
openaire +3 more sources
Biochemical and Biophysical Research Communications, 2005
MicroRNAs (miRNAs), small single-stranded regulatory RNAs capable of interfering with intracellular mRNAs that contain partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. MiRNA was originally discovered in the intergenic regions of the Caenorhabditis elegans genome as native RNA fragments ...
Shao-Yao, Ying, Shi-Lung, Lin
openaire +2 more sources
MicroRNAs (miRNAs), small single-stranded regulatory RNAs capable of interfering with intracellular mRNAs that contain partial complementarity, are useful for the design of new therapies against cancer polymorphism and viral mutation. MiRNA was originally discovered in the intergenic regions of the Caenorhabditis elegans genome as native RNA fragments ...
Shao-Yao, Ying, Shi-Lung, Lin
openaire +2 more sources
Cell Biology International, 2008
AbstractIntrons of plant tubulin genes are useful molecular tools to study IME (Intron Mediated Enhancement of gene expression) and to define plant genetic and evolutionary relationships through ILP (Intron Length Polymorphism). Here we show that the intron present within the 5′UTR sequence of some rice β‐tubulin genes can sustain IME in rice ...
Breviario D +4 more
openaire +5 more sources
AbstractIntrons of plant tubulin genes are useful molecular tools to study IME (Intron Mediated Enhancement of gene expression) and to define plant genetic and evolutionary relationships through ILP (Intron Length Polymorphism). Here we show that the intron present within the 5′UTR sequence of some rice β‐tubulin genes can sustain IME in rice ...
Breviario D +4 more
openaire +5 more sources
Current Biology, 1991
Accumulating evidence that introns are highly restricted in their phylogenetic distribution strongly supports the view that introns were inserted late in eukaryotic evolution into preformed genes and, hence, that exon-shuffling played no role in the assembly of primordial genes.
Jeffrey D. Palmer, John M. Logsdon
openaire +3 more sources
Accumulating evidence that introns are highly restricted in their phylogenetic distribution strongly supports the view that introns were inserted late in eukaryotic evolution into preformed genes and, hence, that exon-shuffling played no role in the assembly of primordial genes.
Jeffrey D. Palmer, John M. Logsdon
openaire +3 more sources
Self-splicing of group I introns.
Annual Review of Biochemistry, 1990PERSPECTlVES . ... . .... .. ..... ... . . ........ . .... ...... .... . ... 543 REACTION PATHWAY ... . . ... ...... . ....... .. ..... . ... . ..... .. . . ...... ... . . . 545 Splicing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
T. Cech
semanticscholar +1 more source
Intron Biology, Focusing on Group II Introns, the Ancestors of Spliceosomal Introns
2015Self-splicing group II introns are large ribozymes and mobile retroelements initially identified in the mitochondrial and chloroplast genomes of lower eukaryotes and plants and subsequently found in bacteria and archaea. Group II introns display structural, functional and mechanistic similarities to eukaryotic pre-mRNA nuclear introns, which may have ...
Francisco Martínez-Abarca +4 more
openaire +2 more sources
Annual Review of Genetics, 2004
Mobile group II introns, found in bacterial and organellar genomes, are both catalytic RNAs and retrotransposable elements. They use an extraordinary mobility mechanism in which the excised intron RNA reverse splices directly into a DNA target site and ...
A. Lambowitz, S. Zimmerly
semanticscholar +1 more source
Mobile group II introns, found in bacterial and organellar genomes, are both catalytic RNAs and retrotransposable elements. They use an extraordinary mobility mechanism in which the excised intron RNA reverse splices directly into a DNA target site and ...
A. Lambowitz, S. Zimmerly
semanticscholar +1 more source
Intron Splicing and Intron-mediated Enhanced Expression in Monocots
1992Publisher Summary The basic recognition sites (5 ‘ , 3‘, and branchpoint) for intron splicing in plants do not differ significantly from those of vertebrates. It is also demonstrated, by the mutations of splice-site recognition sequences, that the 5 ‘ GT or 3‘ AG dinucleotides are essential for proper splicing in monocots.
Ralph M. Sinibaldi, Irvin J. Mettler
openaire +3 more sources