Results 51 to 60 of about 53,015 (296)
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Intrusion detection mechanism and experimental study based on WiFi signal
Indoor safety concerns the safety of people′s life and property. Through indoor intrusion detection, it is possible to achieve early warning and avoid loss. Different from the common intrusion detection methods, the CSI(Channel status information) of the
Zeng Zheng +4 more
doaj +1 more source
Computer Intrusion: Detecting Masquerades
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Schonlau, Matthias +5 more
openaire +4 more sources
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
Intrusion detection system using Online Sequence Extreme Learning Machine (OS-ELM) in advanced metering infrastructure of smart grid. [PDF]
Advanced Metering Infrastructure (AMI) realizes a two-way communication of electricity data through by interconnecting with a computer network as the core component of the smart grid.
Yuancheng Li, Rixuan Qiu, Sitong Jing
doaj +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Network intrusion detection system using supervised learning paradigm
Internet has positively changed social, political and economic structures and in many ways obviating geographical boundaries. The enormous contributions of Internet to business transactions coupled with its ease of use has resulted in increased number of
J. Olamantanmi Mebawondu +3 more
doaj +1 more source
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source

