Results 71 to 80 of about 49,706 (308)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Network intrusion detection system using supervised learning paradigm

open access: yesScientific African, 2020
Internet has positively changed social, political and economic structures and in many ways obviating geographical boundaries. The enormous contributions of Internet to business transactions coupled with its ease of use has resulted in increased number of
J. Olamantanmi Mebawondu   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Intrusion detection system using Online Sequence Extreme Learning Machine (OS-ELM) in advanced metering infrastructure of smart grid. [PDF]

open access: yesPLoS ONE, 2018
Advanced Metering Infrastructure (AMI) realizes a two-way communication of electricity data through by interconnecting with a computer network as the core component of the smart grid.
Yuancheng Li, Rixuan Qiu, Sitong Jing
doaj   +1 more source

Intrusion Detection and Security Assessment in a University Network [PDF]

open access: yes, 2010
This thesis first explores how intrusion detection (ID) techniques can be used to provide an extra security layer for today‟s typically security-unaware Internet user.
Fitzpatrick, Darren
core  

Provenance-based Intrusion Detection Systems: A Survey

open access: yes, 2022
Traditional Intrusion Detection Systems (IDS) cannot cope with the increasing number and sophistication of cyberattacks such as Advanced Persistent Threats (APT).
Zipperle, Michael   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Analysis of Intrusion Detection System

open access: yes, 2020
Intrusion detection plays an important role in ensuring information security, and the key technology is to accurately identify various attacks in the network.
Al-Aodat, Ashraf Mohammad Jadee
core  

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