Results 91 to 100 of about 177,571 (274)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

METHODS ANALYSIS OF INTRUSION DETECTION IN MANET CLASS MOBILE RADIO NETWORKS

Sučasnì Informacìjnì Tehnologìï u Sferì Bezpeki ta Oboroni, 2015
The analysis of existing methods of mobile radio networks intrusion detection was performed in the article and classification of intrusion detection methods was produced.
Serhii V. Salnyk, Oleh Y. Sova, Dmitro A. Minochkin   +2 more
doaj  

A Frequency-Based Approach to Intrusion Detection [PDF]

Journal of Systemics, Cybernetics and Informatics, 2004
Research on network security and intrusion detection strategies presents many challenging issues to both theoreticians and practitioners. Hackers apply an array of intrusion and exploit techniques to cause disruption of normal system operations, but on ...
Mian Zhou, Sheau-Dong Lang
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Design of Intrusion Detection and Response Mechanism for Power Grid SCADA Based on Improved LSTM and FNN

IEEE Access
The current behavior pattern extraction methods in intrusion detection systems cannot fully extract information. To improve the accuracy of such systems, the study first uses sequence feature construction algorithms to explicitly represent sequence ...
Yu Huang, Liangyuan Su
doaj   +1 more source

Review of Key Technologies of Incremental Intrusion Detection for Network Encrypted Traffic [PDF]

Jisuanji gongcheng
As cyber threats continue to intensify, the concealment of encrypted traffic attacks and the suddenness of zero-day exploits have significantly reduced the detection efficiency of traditional intrusion detection systems.
CHEN Liangchen, FU Deyin, LIU Baoxu, GAO Shu, ZHANG Xuyao
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Real-Time Large-Scale Intrusion Detection and Prevention System (IDPS) CICIoT Dataset Traffic Assessment Based on Deep Learning

Applied System Innovation
This research utilizes machine learning (ML), and especially deep learning (DL), techniques for efficient feature extraction of intrusion attacks.
Samuel Kofi Erskine
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source