Results 81 to 90 of about 1,142,874 (336)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Rapid Prototyping of Intrusion Detection Systems [PDF]

open access: yes18th IEEE/IFIP International Workshop on Rapid System Prototyping (RSP '07), 2007
Designing security softwares that evolve as quickly as threats is a truthful challenge. In addition, current software becomes increasingly more complex and difficult to handle even for security experts. Intrusion Detection Softwares (IDS) represent a solution that can alleviate these concerns.
Kordon, Fabrice   +2 more
openaire   +2 more sources

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

Evolving Intrusion Detection Systems [PDF]

open access: yes, 2006
This chapter illustrated the importance of GP techniques for evolving intrusion detection systems. MEP outperforms LGP for three of the considered classes and LGP outperform MEP for two of the classes. MEP classification accuracy is grater than 95% for all considered classes and for three of them is greater than 99.75%.
Ajith Abraham, Crina Grosan
openaire   +2 more sources

Intrusion Detection System for the Internet of Things Based on Blockchain and Multi-Agent Systems

open access: yesElectronics, 2020
With the popularity of Internet of Things (IoT) technology, the security of the IoT network has become an important issue. Traditional intrusion detection systems have their limitations when applied to the IoT network due to resource constraints and the ...
Chao Liang   +7 more
semanticscholar   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An Intrusion Detection System for Internet of Medical Things

open access: yesIEEE Access, 2020
Internet of Things (IoT) is making strong advances in healthcare with the promise of transformation in technological, social and economic prospects, paving the way for a healthy future.
Geethapriya Thamilarasu   +2 more
semanticscholar   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Research on industrial control system intrusion detection method based on simulation modelling

open access: yesTongxin xuebao, 2017
At present,intrusion detection system over fieldbus network layer was a basic protection method in industrial control system.However,it has some weakness,such as poor generality,high false-positive rate,and unable to detect unknown anomaly.An industrial ...
Yi-wei GAO   +5 more
doaj   +2 more sources

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