Results 31 to 40 of about 8,580 (222)

Intratracheal Administration of Dry Powder Formulation in Mice

, 2020
In the development of inhalable dry powder formulations, it is essential to evaluate their biological activities in preclinical animal models. This paper introduces a noninvasive method of intratracheal delivery of dry powder formulation in mice.
LIAO, Q, Lam, JKW, QIU, Y, CHOW, MYT
core   +1 more source

Intratracheal administration of solutions in mice; development and validation of an optimized method with improved efficacy, reproducibility and accuracy [PDF]

, 2022
Animal models are still vital in the field of respiratory disease research. To improve the accuracy and consistency of the dose of specific compounds administered specifically in the respiratory tract, it is important to optimize and to compare the ...
Braber, Saskia, Brans, Maike A D, Afd Pharmacology, Pelgrim, Charlotte E, van Ark, Ingrid, Folkerts, Gert, Leusink-Muis, Thea, Garssen, Johan, van Helvoort, Ardy, Kraneveld, Aletta D, Pharmacology   +10 more
core   +1 more source

Effect of intratracheal dexmedetomidine combined with ropivacaine on postoperative sore throat: a prospective randomised double-blinded controlled trial

BMC Anesthesiology, 2022
Background The present study aimed to investigate whether intratracheal dexmedetomidine combined with ropivacaine reduces the severity and incidence of postoperative sore throat after tracheal intubation under general anaesthesia.
Jingyi Niu, Rui Hu, Na Yang, Yan He, Hao Sun, Rende Ning, Junma Yu   +6 more
doaj   +1 more source

Interventional bronchoscopy for benign tracheobronchial diseases under cardiopulmonary bypass support: case reports and literature review

, 2008
The use of cardiopulmonary bypass as an adjunct to airway surgery for non-malignant diseases in adults is not well established in the UK. We are reporting two cases which demonstrate the additional benefits of using cardiopulmonary bypass during ...
Barnard, Sion, Stephen Clark, Wigfield Christopher H, Clark Stephen, Christopher H. Wigfield, Hussamuddin Adwan, Barnard Sion, Wigfield, Christopher, Adwan Hussamuddin, Sion Barnard, Adwan, Hussamuddin, Clark, Stephen   +11 more
core   +1 more source

Anaesthesia Management of A Patient with Airway Obstruction Caused by Prosthetic Vascular Graft Invasion into the Tracheal Lumen

Turkish Journal of Anaesthesiology and Reanimation
Primary intratracheal masses causing luminal obstruction are relatively rare, posing a challenge for anaesthesiologists in airway management. This case report describes a distinctive airway management approach in a 71-year-old female patient with an ...
Serdar Demirgan, Gülçin Karacan, Sezen Kumaş Solak, Burcu Akyüz, Hakkıcan Akpolat, Ayşin Selcan   +5 more
doaj   +1 more source

Macintosh laryngoscope vs. Pentax-AWS video laryngoscope: comparison of efficacy and cardiovascular responses to tracheal intubation in major burn patients [PDF]

Korean Journal of Anesthesiology, 2012
BackgroundPatients with major burns accompanied with airway edema need more attention for airway management. Although the Pentax-AWS has an advantage in managing endotracheal intubation more easily, its usefulness cannot be assured if it does not ...
Chul-Ho Woo, Sung Hoon Kim, Jae-Young Park, Ji Young Bae, In-Suk Kwak, Sung Ha Mun, Kwang-Min Kim   +6 more
doaj   +1 more source

Comparison of the GlideScope and the McGrath method using vascular forceps and a tube exchanger in cases of simulated difficult airway intubation [PDF]

Korean Journal of Anesthesiology, 2016
BackgroundA "difficult airway" can be simulated with an extrication collar, which restricts cervical motion and mouth opening. The purpose of this study is to compare the efficacy of the GlideScope and the McGrath in difficult airway simulation ...
Jae-Hang Shim, Woo Jae Jeon, Sang Yun Cho, Gyu Ho Choe   +3 more
doaj   +1 more source

Intratracheal aerosolization of viral vectors to newborn pig airways - Supplementary Table 1

, 2020
Supplementary Video 1. Intratracheal aerosolization of viral vectors to newborn pig airways. Video of bronchoscope passing through vocal folds of the larynx and into the trachea.
Patrick L. Sinn (8543754), Ashley L. Cooney (8543751)   +1 more
core   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Budesonide and Surfactant Therapy Versus Surfactant Alone on Incidence of Lung Disease in Preterm Infants (BEST Lung): Study Protocol for a Systematic Review and Individual Participant Data Meta‐Analysis With Nested Prospective Meta‐Analysis

Acta Paediatrica, EarlyView.
ABSTRACT Introduction Bronchopulmonary dysplasia (BPD) is a leading cause of morbidity and mortality in preterm infants. Combining surfactant with budesonide has been proposed to prevent BPD, but results from existing randomised controlled trials (RCTs) are conflicting.
James X. Sotiropoulos, Brett J. Manley, Sol Libesman, Namasivayam Ambalavanan, Abhik Das, Christopher J. D. Mckinlay, Nalinikanta Panigrahy, Melinda Cruz, David Nguyen, Jonathan Williams, Peter Davis, Kylie E. Hunter, Anna Lene Seidler   +12 more
wiley   +1 more source