Results 41 to 50 of about 8,497 (186)
Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae
Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang +10 more
wiley +1 more source
Noninvasive Intratracheal Intubation to Study the Pathology and Physiology of Mouse Lung [PDF]
Journal of Visualized Experiments, 2013 The use of a model that mimics the condition of lung diseases in humans is critical for studying the pathophysiology and/or etiology of a particular disease and for developing therapeutic intervention. With the increasing availability of knockout and transgenic derivatives, together with a vast amount of genetic information, mice provide one of the ...
Yan, Cai, Shioko, Kimura
openaire +2 more sources
Effects of Mesenchymal Stem Cell‐Derived Exosomes on Lung Inflammation in a Murine Aspiration Model
The Laryngoscope, Volume 136, Issue 7, Page 3097-3102, July 2026.This study assessed the effect of intravenous MSC‐derived exosomes on inflammatory lung injury in a rat model of LPS aspiration. Compared with LPS alone, MSC exosome treatment reduced histologic lung injury overall (significant group effect p = 0.02; linear trend p = 0.006) and significantly lowered Tnf gene expression on qRT‐PCR (p < 0.05).
Nogah Nativ‐Zeltzer +5 more
wiley +1 more source
Iranian Journal of Nursing and Midwifery Research, 2020 Background: Usually, the endotracheal tube cuff pressure is controlled by cuff pressure monitoring. However, the intermittent pilot-manometer connection and disconnection may cause a change in the adjusted pressure.
Roghieh Nazari +5 more
doaj +1 more source
Study on the effect of a cold environment on the quality of three video laryngoscopes: McGrath MAC, GlideScope Ranger, and Pentax Airway Scope [PDF]
Clinical and Experimental Emergency Medicine, 2019 Objective Several environmental factors influence the prehospital use of video laryngoscopes (VLs). For example, fogging of the VL lens can occur in cold environments, and the low temperature can cause the VLs to malfunction.
Jin Won Park, Hyuk Joong Choi
doaj +1 more source
Functional Role of Piezo1 in Regulating Whole‐Lung Vascular Reactivity
Pulmonary Circulation, Volume 16, Issue 3, July 2026.ABSTRACT Mechanosensitive cation channels expressed in pulmonary arterial smooth muscle (SMC) and endothelial (EC) cells contribute to the regulation of vasoconstriction and vasodilation of the pulmonary vasculature. Here, we report that activating Piezo1, a mechanosensitive cation channel, with Yoda1 induced a mild increase in pulmonary arterial ...
Sophia Parmisano +17 more
wiley +1 more source
Awake supraglottic airway guided flexible bronchoscopic intubation in patients with anticipated difficult airways: a case series and narrative review [PDF]
Korean Journal of Anesthesiology, 2019 Awake intubation is indicated in difficult airways if attempts at securing the airway after induction of general anesthesia may lead to harm due to potential difficulties or failure in those attempts.
Wan Yen Lim, Patrick Wong
doaj +1 more source
Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu +10 more
wiley +1 more source
MicrobiologyOpen, Volume 15, Issue 3, June 2026.Phage therapy shows promising efficacy against MDR, XDR, and PDR Pseudomonas aeruginosa infections across different models and administration routes. Evidence highlights reduced mortality, bacterial clearance, and synergy with antibiotics, while emphasizing the need for standardized protocols and advanced delivery systems to support clinical ...
Gustavo Aparecido da Cunha +7 more
wiley +1 more source
Evaluation of a Rat Cardiopulmonary Bypass Model Using an Extraluminal Flow Oxygenator
Artificial Organs, Volume 50, Issue 6, Page 825-830, June 2026.A rat cardiopulmonary bypass model was constructed incorporating the developed extraluminal flow oxygenator and compared with a commercial intraluminal flow oxygenator. Both oxygenators demonstrated comparable gas exchange performance and inflammatory responses; however, the one developed in this study better preserved PLT counts.
Hirohito Sumikura +3 more
wiley +1 more source