Results 51 to 60 of about 4,377,369 (241)

Government Subsidies for Industrial Symbiosis: Is It Always Worth It? Assessing Effectiveness and Efficiency Through Agent‐Based Modeling

Business Strategy and the Environment, EarlyView.
ABSTRACT Policy intervention can be a driver for industrial symbiosis (IS). However, given the wide variety of policy instruments available, policymakers should be guided in the policy design process to ensure that their intervention is effective and efficient. In this paper, we propose an agent‐based (AB) model intended to assess the effectiveness and
Melissa Mollica, Alberto Nastasi, Luca Fraccascia   +2 more
wiley   +1 more source

Structure or Composition? Explaining the ESG Premium in Firm Profitability With Oaxaca and Pseudo‐Panel Evidence

Business Strategy and the Environment, EarlyView.
ABSTRACT This study examines whether ESG‐related profitability differences arise from observable firm characteristics or from structural differences in how firms convert those characteristics into performance outcomes. Using an unbalanced panel data design, the final sample comprises 727 firm‐year observations from 178 publicly listed non‐financial ...
Yara Ibrahim, Khaled Hussainey, Taghred Mokhtar Sayed Moawad   +2 more
wiley   +1 more source

Electrochemical Fluorination of Partially Fluorinated Dialkylethers. Synthesis of Sevoflurane Derivatives (CF3)2CHOCHF2, (CF3)2CHOCF3, and (CF3)2CFOCF3

Chemistry – A European Journal, EarlyView.
Electrochemical fluorination (ECF, Simons process) is a valuable method for the fluorination of partially fluorinated dialkyl ethers, providing an inexpensive, scalable, and safe access to partially fluorinated ethers with a higher fluorine content and the perfluorinated analogues that are hardly accessible using other fluorination techniques ...
Tanja Knuplez, Leon N. Schneider, Erik R. Csapo, Peer Kirsch, Nikolai V. Ignat'ev, Maik Finze   +5 more
wiley   +1 more source

Two unbalanced segregation products due to a maternal t(7;16)inv(16)

, 2001
We report a prenatal case of a maternally inherited abnormal chromosome 16, originally interpreted as a pericentric inversion only, but after family studies re-interpreted as a pericentric inversion (16) accompanied by an unbalanced (7;16) translocation.
van der Veen, A., Beike Leegte, Birgit Sikkema‐Raddatz, JanMaarten Cobben, Davelaar, I, Inge Davelaar, Cobben, J, Sikkema-Raddatz, B, Davelaar, [No Value], Hordijk, R, Leegte, B, Roel Hordijk, Anneke van der Veen   +12 more
core   +1 more source

The Governance Gap: Democratizing Drug Development Through Decision Architecture

Clinical Pharmacology &Therapeutics, EarlyView.
Drug development is most exposed to governance failure where it can least afford it, in global health. The field has more predictive power than at any point in its history and roughly the same failure rate it had a decade ago. We argue that this paradox persists because the field has invested heavily in prediction science while neglecting decision ...
Craig R. Rayner, Nancy E. Martin, Danielle Smith, Eliza Kruger, Carl M.J. Kirkpatrick, Goonaseelan (Colin) Pillai, Katy Moore, Darrell Nix, Cristina Donini, Jakob P. Cramer, Edmundo Muniz, Natalia Muniz, Ernst Bos, Douglas McNair, Shyam Bhaskaran, Mark Sullivan, Dan Hartman   +16 more
wiley   +1 more source

An inv(16)(p13q22) positive acute myeloid leukaemia relapsing as acute precursor B-cell lymphoblastic leukaemia

Haematologica, 2004
We describe a case of a 38-year old male with inv(16)(p13q22) positive acute myeloid leukaemia (AML) with eosinophilia, relapsing after a molecular remission of almost three years. Remarkably, the leukaemia at relapse was identified as a precursor-B-cell
N Boeckx, VH van der Velden, M Boogaerts, A Hagemeijer, P Vandenberghe, JJ van Dongen   +5 more
doaj  

Phenotype in combination with genotype improves outcome prediction in acute myeloid leukemia: a report from Children’s Oncology Group protocol AAML0531

Haematologica, 2017
Diagnostic biomarkers can be used to determine relapse risk in acute myeloid leukemia, and certain genetic aberrancies have prognostic relevance. A diagnostic immunophenotypic expression profile, which quantifies the amounts of distinct gene products ...
Andrew P. Voigt, Lisa Eidenschink Brodersen, Todd A. Alonzo, Robert B. Gerbing, Andrew J. Menssen, Elisabeth R. Wilson, Samir Kahwash, Susana C. Raimondi, Betsy A. Hirsch, Alan S. Gamis, Soheil Meshinchi, Denise A. Wells, Michael R. Loken   +12 more
doaj   +1 more source

Natural HDAC‐1/8 inhibitor baicalein exerts therapeutic effect in CBF‐AML

Clinical and Translational Medicine, 2020
Background Although targeting histone deacetylases (HDACs) may be an effective strategy for core binding factor‐acute myeloid leukemia (CBF‐AML) harboring t(8;21) or inv(16), HDAC inhibitors are reported to be limited by drug‐resistant characteristic ...
Xiaoxuan Yu, Hui Li, Po Hu, Yingjie Qing, Xiangyuan Wang, Mengyuan Zhu, Hongzheng Wang, Zhanyu Wang, Jingyan Xu, Qinglong Guo, Hui Hui   +10 more
doaj   +1 more source

Cytogenetic Pattern in Adult Patients with de novo Acute Myeloid Leukaemia: A Single Centre Study in Bangladesh

Haematology Journal of Bangladesh, 2020
Background: Cytogenetic analysis performed at diagnosis is considered to be the most important prognostic factor in AML. Objective: The purpose of this study was to observe the pattern of cytogenetic abnormalities in adult patients with de novo AML ...
Saqi Md. Abdul Baqi, Umme Kulsum Munmun, Md. Rafiquzzaman Khan, Md. Salahuddin Shah, Shafiqul Islam, Farzana Rahman, Md. Abdul Aziz, Masuda Begum   +7 more
doaj   +1 more source

MN1 overexpression is an important step in the development of inv(16) AML

, 2007
The gene encoding the transcriptional co-activator MN1 is the target of the reciprocal chromosome translocation (12;22) (p13;q12) in some patients with acute myeloid leukemia (AML). In addition, expression array analysis showed that MN1 was overexpressed
CARELLA, C., GROSVELD, G. C., Terranova, S, BONTEN, J., Liu, PP, Sirma, S, KRANENBURG, T. A., LIU, P. P., Grosveld, GC (Gerard), Klein-Geltink, R, SHURTLEFF, S., Sirma, Sema, KLEIN-GELTINK, R., Bonten, J, TERRANOVA, S., Carella, C, Downing, JR, Kranenburg, TA, Zwarthoff, Ellen, DOWNING, J. R., ZWARTHOFF, E. C., Shurtleff, S   +21 more
core   +1 more source