Results 61 to 70 of about 1,169,425 (315)

Invasive and non-invasive monitoring in the ICU

open access: yesTrauma Surgery & Acute Care Open
Effective invasive and non-invasive monitoring, when coupled with good clinical decision making, can improve outcomes for critically ill patients. When deciding on the best monitoring technique, it is important to consider the specific information that is needed to guide critical care management, while balancing the reliability of the data obtained and
Kendall R McEachron, Todd W Costantini
openaire   +3 more sources

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Targeting the signaling in Epstein–Barr virus-associated diseases: mechanism, regulation, and clinical study

open access: yesSignal Transduction and Targeted Therapy, 2021
Epstein–Barr virus-associated diseases are important global health concerns. As a group I carcinogen, EBV accounts for 1.5% of human malignances, including both epithelial- and lymphatic-originated tumors.
Ya Cao   +11 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Tumor neoantigen gene C7orf50 remodels the immune microenvironment by recruiting tumor-associated macrophages to promote hepatocellular carcinoma progression and lung metastasis

open access: yesJournal for ImmunoTherapy of Cancer
Background Hepatocellular carcinoma (HCC) is a global health challenge with high mortality rates, particularly in patients with advanced disease and lung metastasis.
Xiaowu Huang   +10 more
doaj   +1 more source

Extracellular matrix collagen I promotes the tumor progression of residual hepatocellular carcinoma after heat treatment

open access: yesBMC Cancer, 2018
Background Accelerated malignant behaviors induced by insufficient thermal ablation have been increasingly reported, however, the exact mechanisms are still unclear. Here, we investigated the importance of the extracellular matrix (ECM) in modulating the
Rui Zhang   +9 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Cancer - from mechanisms of invasion to targeted therapy [PDF]

open access: yes, 2007
Cancer is one of the big challenges of modern medicine. The manifestations of cancer are manifold, and the knowledge of the etiology of cancer is still fragmentary. In order to understand the disease, the complete molecular apparatus and the whole signal
Wicki, Andreas Christian
core   +1 more source

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