Results 81 to 90 of about 1,169,425 (315)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

InaGeedicke/saltmarsh-invasion: First Release of code for saltmarsh invasion manuscript

open access: yes, 2020
This repository contains the code and data for our manuscript "Freshwater input drives invasion success of exotic plants in saltmarsh communities by Geedicke et al.
Ina Geedicke
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Biological invasions in agricultural settings: insights from evolutionary biology and population genetics [PDF]

open access: yes, 2011
Invasion biology and agriculture are intimately related for several reasons and in particular because many agricultural pest species are recent invaders. In this article we suggest that the reconstruction of invasion routes with population genetics-based
Thomas Guillemaud   +12 more
core   +1 more source

A first record of biological soil crusts in the Cape Floristic Region

open access: yesSouth African Journal of Science, 2012
To date, the biological soil crusts (BSCs) of southern Africa are thought to be dominated mainly by cyanobacteria, with the exception of the lichen fields of the Namib Desert.
Denise Mager, Cang Hui
doaj  

Invasive neurostimulation [PDF]

open access: yesThe Journal of Headache and Pain, 2015
Chronic migraine afflicts 1-5% of the global population and poses a substantial burden on subjects’ quality of life and on health services utilization [1]. Although most patients benefit from abortive and preventive drugs, a subgroup of patients remains refractory to treatment. Refractory chronic migraine is one of the greatest chal- lenges in headache
MERCIERI, MARCO   +9 more
openaire   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Invasion success of a global avian invader is explained by within-taxon niche structure and association with humans in the native range [PDF]

open access: yes, 2015
Aim To mitigate the threat invasive species pose to ecosystem functioning, reli- able risk assessment is paramount. Spatially explicit predictions of invasion risk obtained through bioclimatic envelope models calibrated with native species distribution ...
Strubbe, Diederik   +8 more
core   +1 more source

The invasion of circRNAs [PDF]

open access: yesRNA Biology, 2017
Single-stranded covalently closed circular RNA (circRNA) molecules come in many disguises, with different biogenesis mechanisms and functions.
Thomas B, Hansen, Jørgen, Kjems
openaire   +2 more sources

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