Results 101 to 110 of about 1,169,425 (315)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

On Prevention and Control of an Uncertain Biological Invasion [PDF]

This paper examines how optimal prevention and control policies depend on the economic and biological characteristics of a randomly introduced biological invasion where the objective is to minimize the expected social costs from prevention, control, and ...
Olson, Lars J., Roy, Santanu
core  

Molecular mechanisms of drug resistance, invasion and metastasis in pancreatic carcinoma [PDF]

, 2008
The research outlined in this thesis aims to further our knowledge of the biological characteristics underlying the aggressive behaviour by which pancreatic cancer invades and metastasises at an early stage and is refractory to most chemotherapeutic ...
Walsh, Naomi
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Taming the terminological tempest in invasion science [PDF]

Standardised terminology in science is important for clarity of interpretation and communication. In invasion science – a dynamic and rapidly evolving discipline – the proliferation of technical terminology has lacked a standardised framework for its ...
Glavendekic, M.M., Simberloff, D., Meshkova, V., Patoka, J., Florencio, M., Soto, I., Britton, J.R., Zenni, R.D., South, J., Oficialdegui, F.J., López‐López, E., Cano‐Barbacil, C., Yapıcı, S., Bradshaw, C.J.A., Macêdo, R., Falk‐Andersson, J., Nuñez, M.A., Ahmed, D.A., Bacela‐Spychalska, K., Piria, M., Stoett, P., Buřič, M., Vilizzi, L., Musolin, D.L., Dick, J.T.A., Balzani, P., Camacho‐Cervantes, M., Kirichenko, N.I., Fernandez, R.D., Bortolus, A., De Santis, V., Pattison, Z., Coughlan, N.E., Sanchez, A.E., Carneiro, L., Weiperth, A., Cuthbert, R.N., Rilov, G., Baudry, T., Milardi, M., Wang, Y., Watari, Y., Liu, C., Lozano, V., Ballesteros‐Mejia, L., Franco, A.C.S., Kourantidou, M., Dimarco, R.D., Courtois, P., Herrera, I., Robinson, T.B., Lipták, B., Kurtul, I., Mammola, S., Briski, E., Probert, A.F., Russell, J.C., Marchini, A., Wehi, P.M., Wiberg‐Larsen, P., Laufer, G., Grabowski, M., Ricciardi, A., Rasmussen, J.J., Huang, W., Schwindt, E., Galil, B.S., Renault, D., Bang, A., Dalu, T., Bailey, S.A., Csabai, Z., Dickey, J.W.E., Verreycken, H., Yoğurtçuoğlu, B., Serhan Tarkan, A., Haubrock, P.J., Pincheira‐Donoso, D., Copilaș‐Ciocianu, D., Giannetto, D., Ribeiro, F., Heringer, G., García‐Berthou, E., Kamelamela, K.L., Kouba, A.   +84 more
core   +1 more source

MODELLING THE INFLUENCE OF NUCLEUS ELASTICITY ON CELL INVASION IN FIBER NETWORKS AND MICROCHANNELS [PDF]

, 2013
Cell migration in highly constrained extracellular matrices is exploited in scaffold-based tissue engineering and is fundamental in a wide variety of physiological and pathological phenomena, among others in cancer invasion and development. Research into
Scianna, Marco, Preziosi, Luigi
core   +1 more source

Heterospecific social interactions of the invasive guppy (Poecilia reticulata): a potential trait to enhance invasion success [PDF]

, 2015
Electronic version excludes material for which permission has not been granted by the rights holderFrom all the species that arrive to a novel environment, very few manage to form a viable population.
Camacho-Cervantes, Morelia
core   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Invasion theory and biological control. [PDF]

, 2002
Recent advances in the mathematical theory of invasion dynamics have much to offer to biological control. Here we synthesize several results concerning the spatiotemporal dynamics that occur when a biocontrol agent spreads into a population of an ...
Neubert, M. G., Lewis, M. A., Fagan, W. F.   +2 more
core   +1 more source