Results 101 to 110 of about 1,492,047 (368)

Alien species in South Africa’s national parks

Koedoe: African Protected Area Conservation and Science, 2011
Alien species in South Africa’s national ...
Dian Spear, Melodie A. McGeoch, Llewellyn C. Foxcroft, Hugo Bezuidenhout   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

On Prevention and Control of an Uncertain Biological Invasion [PDF]

This paper examines how optimal prevention and control policies depend on the economic and biological characteristics of a randomly introduced biological invasion where the objective is to minimize the expected social costs from prevention, control, and ...
Olson, Lars J., Roy, Santanu
core   +1 more source

Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]

, 2010
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Muller, DN, Cartwright, JE, Pijnenborg, R, Pijnenborg, R., Stefan Verlohren, Luft, F.C., Mueller, D.N., Lydia Hering, Morton, J., Davidge, ST, Dechend, R, Geusens, N, Robert Pijnenborg, Herse, F, Judith E. Cartwright, Herse, F., Florian Herse, Ralf Dechend, Dudenhausen, J.W., Nele Geusens, Cartwright, J.E., Geusens, N., Verhaegen, I., Jude Morton, Morton, J, Hering, L, Iris Verhaegen, Dominik N. Muller, Dechend, R., Sandra T. Davidge, Joachim W. Dudenhausen, Hering, L., Davidge, S.T., Verlohren, S, Verhaegen, I, Dudenhausen, JW, Friedrich C. Luft, Verlohren, S., Luft, FC   +38 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Cystatin C Expression is Promoted by VEGFA Blocking, With Inhibitory Effects on Endothelial Cell Angiogenic Functions Including Proliferation, Migration, and Chorioallantoic Membrane Angiogenesis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
Background Vascular development, including vasculogenesis and angiogenesis, is involved in many diseases. Cystatin C (CST3) is a commonly used marker of renal dysfunction, and we have previously reported that its expression level is associated with ...
Zhenkun Li, Shiyuan Wang, Xueyun Huo, Hefen Yu, Jing Lu, Shuangyue Zhang, Xiaohong Li, Qi Cao, Changlong Li, Meng Guo, Jianyi Lv, Xiaoyan Du, Zhenwen Chen   +12 more
doaj   +1 more source

MicroRNA-96-5p promotes proliferation, invasion and EMT of oral carcinoma cells by directly targeting FOXF2 [PDF]

, 2020
Haiyan Wang, Ning Ma, Wenyue Li, Zuomin Wang   +3 more
openalex   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Taming the terminological tempest in invasion science [PDF]

Standardised terminology in science is important for clarity of interpretation and communication. In invasion science – a dynamic and rapidly evolving discipline – the proliferation of technical terminology has lacked a standardised framework for its ...
Glavendekic, M.M., Simberloff, D., Meshkova, V., Patoka, J., Florencio, M., Soto, I., Britton, J.R., Zenni, R.D., South, J., Oficialdegui, F.J., López‐López, E., Cano‐Barbacil, C., Yapıcı, S., Bradshaw, C.J.A., Macêdo, R., Falk‐Andersson, J., Nuñez, M.A., Ahmed, D.A., Bacela‐Spychalska, K., Piria, M., Stoett, P., Buřič, M., Vilizzi, L., Musolin, D.L., Dick, J.T.A., Balzani, P., Camacho‐Cervantes, M., Kirichenko, N.I., Fernandez, R.D., Bortolus, A., De Santis, V., Pattison, Z., Coughlan, N.E., Sanchez, A.E., Carneiro, L., Weiperth, A., Cuthbert, R.N., Rilov, G., Baudry, T., Milardi, M., Wang, Y., Watari, Y., Liu, C., Lozano, V., Ballesteros‐Mejia, L., Franco, A.C.S., Kourantidou, M., Dimarco, R.D., Courtois, P., Herrera, I., Robinson, T.B., Lipták, B., Kurtul, I., Mammola, S., Briski, E., Probert, A.F., Russell, J.C., Marchini, A., Wehi, P.M., Wiberg‐Larsen, P., Laufer, G., Grabowski, M., Ricciardi, A., Rasmussen, J.J., Huang, W., Schwindt, E., Galil, B.S., Renault, D., Bang, A., Dalu, T., Bailey, S.A., Csabai, Z., Dickey, J.W.E., Verreycken, H., Yoğurtçuoğlu, B., Serhan Tarkan, A., Haubrock, P.J., Pincheira‐Donoso, D., Copilaș‐Ciocianu, D., Giannetto, D., Ribeiro, F., Heringer, G., García‐Berthou, E., Kamelamela, K.L., Kouba, A.   +84 more
core   +1 more source