Results 121 to 130 of about 1,492,047 (368)

Invasion Mechanisms of Bladder Cancer: A Molecular Review [PDF]

open access: yes, 2016
Bladder cancer (BC) is a very common cancer and it has high mortality rates, especially in late stages. BC is considered as a different disease in various stages and grades. Non-muscle-invasive BC and muscle-invasive BC have different properties.
Kamil Fehmi Narter, Kubilay Sabuncu
core   +1 more source

Transabdominal Ultrasound Measurement of the Diameter of Rectal Ampulla as a Less Invasive Modality for Digital Rectal Examination in Children with Functional Constipation [PDF]

open access: diamond, 2022
Farid Imanzadeh   +11 more
openalex   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Invasion science for society: A decade of contributions from the Centre for Invasion Biology

open access: yesSouth African Journal of Science, 2014
Biological invasions are a growing problem worldwide. In 2004, the South African Department of Science and Technology, through the National Research Foundation, established a Centre of Excellence for Invasion Biology, with the primary goal of providing ...
Brian W. van Wilgen   +2 more
doaj   +1 more source

MODELLING THE INFLUENCE OF NUCLEUS ELASTICITY ON CELL INVASION IN FIBER NETWORKS AND MICROCHANNELS [PDF]

open access: yes, 2013
Cell migration in highly constrained extracellular matrices is exploited in scaffold-based tissue engineering and is fundamental in a wide variety of physiological and pathological phenomena, among others in cancer invasion and development. Research into
Scianna, Marco, Preziosi, Luigi
core   +1 more source

Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite [PDF]

open access: bronze, 2007
Jürgen Bosch   +8 more
openalex   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Invasive neighbors

open access: yesBlood, 2013
n ...
Paolini, Ambra, Bonacorsi, Goretta
openaire   +3 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The implications of signaling lipids in cancer metastasis

open access: yesExperimental and Molecular Medicine, 2018
Cancer treatment: Targeting or Modifying lipids with signaling role Lipid molecules with cellular signaling roles are increasingly recognized as playing a role in cancer metastasis, the dangerous spread of cancer cells beyond a primary tumor, and these ...
Xiangjian Luo   +5 more
doaj   +1 more source

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