Results 141 to 150 of about 1,492,047 (368)
The influence of vegetation structure and composition on invasibility by Pinus radiata in the Blue Mountains, NSW [PDF]
, 2013 The exotic tree species Pinus radiata D. Don (in the family Pinaceae) has successfully spread from commercial plantations into adjacent vegetation in southeastern Australia.
Williams, Moira C., Wardle, Glenda M.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Ecology and EvolutionGlobal warming has significantly accelerated the invasion process and expanded the distribution range of Solidago canadensis. It forms a dominant monoculture in multiple regions via wind‐dispersed seeds and rhizome clonal propagation, posing a serious ...
Jinghui Zhang +10 more
doaj +1 more source
Mesenchymal Stem Cells Promote Invasion in Salivary Mesenchymal Stem Cells Promote Invasion in Salivary [PDF]
, 2012 Mesenchymal Stem Cells Promote Invasion in Salivary Mesenchymal Stem Cells Promote Invasion in ...
张敏, 马慧朋, 秦建华
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Microvascular Invasion in Hepatocellular Carcinoma: Some Puzzling Facets [PDF]
Background/Aims: Hepatocellular carcinoma is the main type of primary liver cancer. Macroscopic vascular invasion is usually identified during imaging, whereas microvascular invasion is usually determined by histopathological evaluation.
Brian I Carr +5 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Ecology and EvolutionThe Aulacophora beetles are pests closely associated with cucurbit plants. However, research on the fine‐scale population genetics of species within this genus remains limited. This study employed mitogenome data from 211 individuals (102 A.
Bo He +8 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source