Results 131 to 140 of about 304,649 (268)

On Prevention and Control of an Uncertain Biological Invasion

This paper examines how optimal prevention and control policies depend on the economic and biological characteristics of a randomly introduced biological invasion where the objective is to minimize the expected social costs from prevention, control, and ...
Olson, Lars J., Roy, Santanu
core  

Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy.

, 2010
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Muller, DN, Cartwright, JE, Pijnenborg, R, Pijnenborg, R., Stefan Verlohren, Luft, F.C., Mueller, D.N., Lydia Hering, Morton, J., Davidge, ST, Dechend, R, Geusens, N, Robert Pijnenborg, Herse, F, Judith E. Cartwright, Herse, F., Florian Herse, Ralf Dechend, Dudenhausen, J.W., Nele Geusens, Cartwright, J.E., Geusens, N., Verhaegen, I., Jude Morton, Morton, J, Hering, L, Iris Verhaegen, Dominik N. Muller, Dechend, R., Sandra T. Davidge, Joachim W. Dudenhausen, Hering, L., Davidge, S.T., Verlohren, S, Verhaegen, I, Dudenhausen, JW, Friedrich C. Luft, Verlohren, S., Luft, FC   +38 more
core   +1 more source

Phragmites australis and Argyrogramma albostriata Suppress the Invasion of Solidago canadensis in China Under Future Climate Change

Ecology and Evolution
Global warming has significantly accelerated the invasion process and expanded the distribution range of Solidago canadensis. It forms a dominant monoculture in multiple regions via wind‐dispersed seeds and rhizome clonal propagation, posing a serious ...
Jinghui Zhang, Xiaoying Xiao, Wei Huang, Yuxin Huo, Yuxin Zhang, Shujian Zhang, Xinyi Huang, Muhammad Umair Hassan, Yuxi Xue, Qitao Su, Yian Xiao   +10 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Author Correction: GPR162 activates STING dependent DNA damage pathway as a novel tumor suppressor and radiation sensitizer

Signal Transduction and Targeted Therapy, 2023
Yao Long, Jiaxing Guo, Jielin Chen, Jingyue Sun, Haiyan Wang, Xin Peng, Zuli Wang, WeiWei Lai, Na Liu, Long Shu, Ling Chen, Ying Shi, Desheng Xiao, Shuang Liu, Yongguang Tao   +14 more
doaj   +1 more source

A Method for Conveying Confidence in iNaturalist Observations: A Case Study Using Non‐Native Marine Species

Ecology and Evolution
Concerns and limitations relating to data quality, reliability and accuracy hamper the use of citizen science initiatives in research and conservation. Valued for their cost‐effective and large data acquisition potential, citizen science platforms such ...
Sarah J. Ackland, David M. Richardson, Tamara B. Robinson   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Population Genetic Differences Between Two Cucurbit Leaf Beetles With Contrasting Feeding Preferences

Ecology and Evolution
The Aulacophora beetles are pests closely associated with cucurbit plants. However, research on the fine‐scale population genetics of species within this genus remains limited. This study employed mitogenome data from 211 individuals (102 A.
Bo He, Mingkang Xiao, Tianyu Ye, Gonghua Lin, Fang Zhao, Liancheng Liu, Huanhuan Li, Tianjuan Su, Zuhao Huang   +8 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source