Altered placental expression of kisspeptin and its receptor in pre-eclampsia [PDF]
Kisspeptin, originally identified as metastatin, important in preventing cancer metastasis, has more recently been shown to be important in pregnancy.
Williams, Paula Juliet +3 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The effects of an invasive alien plant (Chromolaena odorata) on large African mammals
Alien plants have invaded most ecosystem types (terrestrial, fresh water and marine) and are responsible for the loss of irreplaceable natural services on which humankind relies.
Lihle Dumalisile, Michael J. Somers
doaj +1 more source
Endometrial biology during trophoblast invasion
Attainment of successful implantation depends upon the synchronized changes in the endometrium before and after the arrival of blastocyst into the uterine cavity. The cues obtained from the receptive endometrium helps in proliferation and differentiation of the trophoblast cells.
Deepak Narhari, Modi +3 more
openaire +2 more sources
Contribution of 3q26-29 gene cluster to glioma invasion [PDF]
Diffuse gliomas are the most common and lethal brain tumors. Cell invasion into the surrounding brain tissue is a hallmark feature of glioma. Understanding the mechanism of glioma invasion could lead to the discovery of novel therapeutic strategies to ...
Ramadoss, Archana
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Assessing water conditions for Heleophryne rosei tadpoles and the conservation relevance
The Table Mountain Ghost Frog (Heleophryne rosei) is endemic to the Table Mountain massif and is Critically Endangered. Other than clear, clean perennial stream flow, the optimal aquatic conditions required by their larvae are unknown.
Zishan Ebrahim +2 more
doaj +1 more source
Transcriptional regulation of the urokinase receptor (u-PAR) - A central molecule of invasion and metastasis [PDF]
The phenomenon of tumor-associated proteolysis has been acknowledged as a decisive step in the progression of cancer. This short review focuses on the urokinase receptor (u-PAR), a central molecule involved in tumor-associated invasion and metastasis ...
Fuchs, T., Allgayer, H.
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Community science can inform invasive species management: Melaleuca (Myrtaceae) in South Africa
Community science initiatives are revolutionising our ability to detect and respond to biological invasions. Non‐native trees and shrubs are among the world's most damaging invasive species and community science data can be used to inform protocols for ...
Luke J. Potgieter +2 more
doaj +1 more source

