Results 111 to 120 of about 1,910,351 (302)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Bothalia: African Biodiversity & Conservation, 2019 Background: Many alien plant species, such as Tithonia diversifolia, T. rotundifolia and T. tubaeformis, have been introduced to areas outside of their natural distribution range to provide benefits, but have subsequently become invasive, threatening ...
Arne B.R. Witt +4 more
doaj +1 more source
Trends in the direction of global plant invasion biology research over the past two decades. [PDF]
Ecol Evol, 2023 Chiu JH, Chong KY, Lum SKY, Wardle DA.
europepmc +1 more source
Framing and Reframing in Invasion Biology
Configurations, 2008 In this essay, we focus on metaphors in invasion biology. The emergence of this discipline went hand in hand with heated debates on the so-called exotic species issue. The dualistic stalemate in which these debates have resulted—with only two extreme positions, nativism on the one hand and cosmopolitanism on the other—is at least partly connected ...
Keulartz, F.W.J., van der Weele, C.N.
openaire +1 more source
Biology and interspecific interactions of the alien crab Percnon gibbesi in the Maltese Islands [PDF]
, 2008 Spatial and bathymetric distribution, population density, habitat preferences, fecundity, breeding season and interspecific interactions of the alien grapsoid crab Percnon gibbesi (H.
Sciberras, Marija +2 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
An assessment of the information content of South African alien species databases
Bothalia: African Biodiversity & Conservation, 2015 National alien species databases indicate the state of a country’s biodiversity and provide useful data for research on invasion biology and the management of invasions.
Katelyn T. Faulkner +4 more
doaj +1 more source
Plasmodium falciparum:Rosettes do not protect merozoites from invasion-inhibitory antibodies [PDF]
, 2006 Rosetting is a parasite adhesion phenotype associated with severe malaria in African children. Why parasites form rosettes is unknown, although enhanced invasion or immune evasion have been suggested as possible functions.
Rowe, J Alexandra; id_orcid +1 more
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Biphasic behaviour in malignant invasion [PDF]
, 2006 Invasion is an important facet of malignant growth that enables tumour cells to colonise adjacent regions of normal tissue. Factors known to influence such invasion include the rate at which the tumour cells produce tissue-degrading molecules, or ...
Norbury, J. +8 more
core +1 more source