Results 51 to 60 of about 1,910,351 (302)

Are We Ready for Migrastatics?

open access: yesCells, 2021
Metastasis accounts for the highest mortality rates in solid tumor cancer patients. However, research and development have neglected this most lethal characteristic and, instead, have concentrated on the hallmarks of cancer that make tumor cells highly ...
Jonathan Solomon   +4 more
doaj   +1 more source

Biology of invasive mucinous adenocarcinoma of the lung [PDF]

open access: yesTranslational Lung Cancer Research, 2017
Invasive mucinous adenocarcinoma (IMA) is a unique histologic subtype of lung adenocarcinoma. Recent studies document distinctive genetic alterations (e.g., NRG1 fusions) and a "mucinous gene signature" in IMAs, as well as differences in clinical responses to traditional chemotherapies in IMAs versus non-mucinous adenocarcinomas.
Yoon Jin, Cha, Hyo Sup, Shim
openaire   +3 more sources

Support for major hypotheses in invasion biology is uneven and declining [PDF]

open access: yes, 2012
Several major hypotheses have been proposed to explain and predict biological invasions, but the general applicability of these hypotheses is largely unknown, as most of them have not been evaluated using a standard approach across taxonomic groups and ...
Strayer,David   +27 more
core   +1 more source

MODELLING THE INFLUENCE OF NUCLEUS ELASTICITY ON CELL INVASION IN FIBER NETWORKS AND MICROCHANNELS [PDF]

open access: yes, 2013
Cell migration in highly constrained extracellular matrices is exploited in scaffold-based tissue engineering and is fundamental in a wide variety of physiological and pathological phenomena, among others in cancer invasion and development. Research into
Scianna, Marco, Preziosi, Luigi
core   +1 more source

Flight-reproduction trade-offs are weak in a field cage experiment across multiple Drosophila species

open access: yesCurrent Research in Insect Science, 2023
Flight-reproduction trade-offs, such that more mobile individuals sacrifice reproductive output (e.g., fecundity) or incur fitness costs, are well-studied in a handful of wing-dimorphic model systems.
Liana I. De Araujo   +2 more
doaj   +1 more source

A small-molecule inhibitor of T. gondii motility induces the posttranslational modification of myosin light chain-1 and inhibits myosin motor activity [PDF]

open access: yes, 2010
Toxoplasma gondii is an obligate intracellular parasite that enters cells by a process of active penetration. Host cell penetration and parasite motility are driven by a myosin motor complex consisting of four known proteins: TgMyoA, an unconventional ...
Carey, Kimberly L.   +15 more
core   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

An agenda for invasion biology [PDF]

open access: yesBiological Conservation, 1996
Here I advocate a comparative and systematic approach in which invasion (the extension of species ranges to areas not previously occupied by that species) is studied from the perspective of individual species as well as of the regions and biotas that export and receive invaders. In order to go beyond the particulars of invasion, it is important to ask:
openaire   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan   +18 more
wiley   +1 more source

Do trophic subsidies affect the outcome of introductions of a non-native freshwater fish? [PDF]

open access: yes, 2013
Understanding how environmental variables and human disturbances influence the outcomes of introductions of non-native freshwater fish is integral to their risk management. This can be complex in freshwater ecosystems that receive subsidies that increase
Allen, R.   +7 more
core   +1 more source

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