Results 61 to 70 of about 1,910,351 (302)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Invasion biology deconstructed [PDF]
Trends in Ecology & Evolution, 2009 Charles Elton's 1958 book The Ecology of Invasions by Animals and Plants [1] is widely acknowledged as having kick-started the systematic scientific study of biological invasions. In the fifty years since Elton's book appeared, the scale and complexity of invasions has escalated to the point that few field ecologists can now avoid considering ...
openaire +1 more source
Invasion and persistence of infectious agents in fragmented host populations [PDF]
, 2011 One of the important questions in understanding infectious diseases and their prevention and control is how infectious agents can invade and become endemic in a host population.
Heesterbeek, J.A.P. +15 more
core +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Mathematical modeling of tumor growth and treatment [PDF]
, 2014 Using mathematical models to simulate dynamic biological processes has a long history. Over the past couple of decades or so, quantitative approaches have also made their way into cancer research.
Chaplain, Mark A. J., Enderling, Heiko
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Ecology and Society, 2012 The Table Mountain National Park is a 265 km2 protected area embedded within a city of 3.5 million people. The park contains an extremely diverse flora with many endemic species, and has been granted World Heritage Site status in recognition of this ...
Brian W. van Wilgen
doaj +1 more source
Wolbachia: Invasion Biology in South Pacific Butterflies [PDF]
Current Biology, 2007 Wolbachia ensdosymbionts are well known for their ability to manipulate the population biology and development of their hosts. One of the less studied outcomes of Wolbachia infection with this symbiont is the selective killing of male embryos. Recent work on butterflies living on different South Pacific islands is beginning to help us understand the ...
McGraw, Elizabeth A. +1 more
openaire +5 more sources
Secondary contact and admixture between independently invading populations of the Western corn rootworm, diabrotica virgifera virgifera in Europe [PDF]
, 2012 The western corn rootworm, Diabrotica virgifera virgifera (Coleoptera: Chrysomelidae), is one of the most destructive pests of corn in North America and is currently invading Europe.
Thomas Guillemaud +39 more
core +1 more source