The admixed brushtail possum genome reveals invasion history in New Zealand and novel imprinted genes. [PDF]
Bond DM +25 more
europepmc +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Population Genomic Evidence of Adaptive Response during the Invasion History of Plasmodium falciparum in the Americas. [PDF]
Lefebvre MJM +5 more
europepmc +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Ecology, invasion history and biodiversity-driven management of the coconut black-headed caterpillar Opisina arenosella in Asia. [PDF]
Lu H +8 more
europepmc +1 more source
The general who orchestrated the greatest amphibian invasion in history, and led Allied forces in the great crusade to crush Adolf Hitler’s armies, subsequently became a popular two-term president of the United States.
Birkner, Michael J., McKinney, Devin
core
The Role and Work of Bomber Command: A Note by Air Marshal Sir Arthur Harris for the Prime Minister and Cabinet, 28 June 1942 [PDF]
Editor’s Note: Few senior Allied Commanders have been criticized as strongly as Air Marshal Sir Arthur Harris. And even those critics who recognize the vital contribution Harris and the Bomber Command made to the defeat of Nazi Germany are disturbed by ...
Harris, Arthur
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Public Opinion and National Prestige: The Politics of Canadian Army Participation to the Invasion of Sicily, 1942–1943 [PDF]
The participation of Canadian troops in the Sicilian campaign of July and August 1943 marked a distinctive shift in Canada’s war policy, and significantly influenced the employment of the army until the end of hostilities in May 1945.
Barton, Brandey
core +1 more source

