Results 101 to 110 of about 598 (250)
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Identifying Priorities, Targets, and Actions for the Long-term Social and Ecological Management of Invasive Non-Native Species. [PDF]
García-Díaz P +22 more
europepmc +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
La cronología de las cuevas artificiales
El principal problema en el estudio de las cuevas artificiales ha sido hasta ahora el establecimiento de las fechas para todo el fenómeno y para cada cueva en concreto.
Antonino González Blanco
doaj
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
La situación nacional era especialmente tensa. Como sucede en Colombia tantas veces cuando los observadores afirman: “Esto no puede durar más”. Grave conflicto universitario, amenaza de un “paro nacional” por parte de la Unión de Trabajadores Colombianos
Oscar Jaramillo, S.J.
doaj
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
La creciente amenaza de las invasiones biológicas
Muchas especies de plantas y animales son transportadas voluntaria o involuntariamente fuera de su área original por los seres humanos. Algunas de ellas pueden desplazar a las autóctonas, interfiriendo en el funcionamiento de los ecosistemas receptores.
P. Castro Díez +2 more
doaj

