Results 21 to 30 of about 22,723 (179)

Clinico-immunological features of invasive aspergillosis in patients with Hodgkin’s disease

Клиническая онкогематология, 2014
Invasive aspergillosis is a serious mycotic infection with high mortality that mostly occurs in patients with hematological malignancies and severe immunodeficiency.
O. V. Shadrivova, Ye. V. Frolova, L. V. Filippova, A. Ye. Uchevatkina, S. N. Khostelidi, R. M. Chernopyatova, Ye. A. Desyatik, A. G. Volkova, Ye. V. Shagdileyeva, L. S. Zubarovskaya, A. V. Rysev, S. M. Ignatyeva, T. S. Bogomolova, Yu. N. Vinogradova, N. V. Vasilyeva, N. N. Klimko   +15 more
doaj   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

Angewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma, Komal Sharma, Anku Sharma, Kamya Rao, Rahul Jain, Brett VanVeller   +5 more
wiley   +2 more sources

Invasive aspergillosis in patients with hematologic malignancies: incidence and description of 127 cases enrolled in a single institution prospective survey from 2004 to 2009

Haematologica, 2011
Background The study objectives were: 1) to report on invasive aspergillosis patients in a hematology department; and 2) to estimate its incidence according to the hematologic diagnosis.Design and Methods A prospective survey of invasive aspergillosis ...
Marie-Christine Nicolle, Thomas Bénet, Anne Thiebaut, Anne-Lise Bienvenu, Nicolas Voirin, Antoine Duclos, Mohamad Sobh, Giovanna Cannas, Xavier Thomas, Frank-Emmanuel Nicolini, Frédérique De Monbrison, Marie-Antoinette Piens, Stéphane Picot, Mauricette Michallet, Philippe Vanhems   +14 more
doaj   +1 more source

Recovery of a triazole-resistant Aspergillus fumigatus in respiratory specimen of COVID-19 patient in ICU – A case report

Medical Mycology Case Reports, 2021
Although invasive pulmonary aspergillosis (IPA) is typically described in immunocompromised host, patient with severe influenzae can develop IPA. Similarly, patients with severe COVID-19 complicated with IPA are increasingly reported. Here, we describe a
Théo Ghelfenstein-Ferreira, Anastasia Saade, Alexandre Alanio, Stéphane Bretagne, Raffael Araujo de Castro, Samia Hamane, Elie Azoulay, Swann Bredin, Sarah Dellière   +8 more
doaj   +1 more source

A case of CNS aspergillosis in a patient with chronic lymphocytic leukemia on first-line ibrutinib therapy

Medical Mycology Case Reports, 2020
Ibrutinib has revolutionized the treatment of chronic lymphoid malignancies. Despite its success, ibrutinib has been linked with several reports of invasive fungal infections.
Emily M. Eichenberger, Jennifer Saullo, Danielle Brander, Shih-Hsiu Wang, John R. Perfect, Julia A. Messina   +5 more
doaj   +1 more source

Influence of polymorphisms in innate immunity genes on susceptibility to invasive aspergillosis after stem cell transplantation. [PDF]

PLoS ONE, 2011
The innate immune system plays a pivotal role in the primary defence against invasive fungal infection. Genetic variation in genes that regulate this response, initiated by pulmonary macrophages, may influence susceptibility to invasive aspergillosis in ...
Mark G J de Boer, Hetty Jolink, Constantijn J M Halkes, Pim L J van der Heiden, Dennis Kremer, J H Frederik Falkenburg, Esther van de Vosse, Jaap T van Dissel   +7 more
doaj   +1 more source

Characteristics and Outcomes of Patients with Invasive Pulmonary Aspergillosis and Respiratory Tract Aspergillus Colonization from a Tertiary University Hospital in Thailand

Journal of Fungi, 2022
Positive culture for Aspergillus spp. from respiratory specimens needs to be interpreted together with relevant clinical conditions/settings to differentiate invasive infection from colonization.
Pannathat Soontrapa, Piriyaporn Chongtrakool, Methee Chayakulkeeree   +2 more
doaj   +1 more source

Immunogenetics of invasive aspergillosis [PDF]

Medical Mycology, 2011
Invasive aspergillosis is one of the most important infections in hematopoietic stem cell transplant recipients, with an incidence rate of 5-15% and an associated mortality of 30-60%. It remains unclear why certain patients develop invasive aspergillosis while others, undergoing identical transplant regimen and similar post transplant immunosuppression,
Lamoth Frédéric, Rubino Ivana, Bochud Pierre-Yves   +2 more
openaire   +3 more sources

Donor-derived invasive aspergillosis after kidney transplant

Medical Mycology Case Reports, 2018
The risk of transmission of infectious diseases from allograft to recipient is well known. Viruses and bacteria are the most frequent causes of transmissible infections.
Maricela Valerio, Marina Machado, Santiago Cedeño, Maria Luisa Rodríguez, Fernando Anaya, Antonio Vena, Jesús Guinea, Pilar Escribano, Emilio Bouza, Patricia Muñoz   +9 more
doaj   +1 more source

Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development [PDF]

Reviews in Clinical Medicine, 2020
Aspergillosis is a common fungal infection with systemic characteristics, which is caused by various species of Aspergillus. The infection could develop in immunocompromised and immunocompetent patients under specific circumstances. Based on the clinical
Ali AL-Janabi
doaj   +1 more source