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Although invasive pulmonary aspergillosis (IPA) is typically described in immunocompromised host, patient with severe influenzae can develop IPA. Similarly, patients with severe COVID-19 complicated with IPA are increasingly reported. Here, we describe a
Théo Ghelfenstein-Ferreira +8 more
doaj +1 more source
Ibrutinib has revolutionized the treatment of chronic lymphoid malignancies. Despite its success, ibrutinib has been linked with several reports of invasive fungal infections.
Emily M. Eichenberger +5 more
doaj +1 more source
Influence of polymorphisms in innate immunity genes on susceptibility to invasive aspergillosis after stem cell transplantation. [PDF]
The innate immune system plays a pivotal role in the primary defence against invasive fungal infection. Genetic variation in genes that regulate this response, initiated by pulmonary macrophages, may influence susceptibility to invasive aspergillosis in ...
Mark G J de Boer +7 more
doaj +1 more source
Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients [PDF]
Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients
Lehrnbecher, Thomas +11 more
core +1 more source
How Do I Manage Refractory Invasive Pulmonary Aspergillosis. [PDF]
BACKGROUND Invasive aspergillosis is associated with significant morbidity and mortality in patients with hematologic malignancies and hematopoietic cell transplant recipients.
Nguyen, M Hong +3 more
core +2 more sources
Positive culture for Aspergillus spp. from respiratory specimens needs to be interpreted together with relevant clinical conditions/settings to differentiate invasive infection from colonization.
Pannathat Soontrapa +2 more
doaj +1 more source
Immunogenetics of invasive aspergillosis [PDF]
Invasive aspergillosis is one of the most important infections in hematopoietic stem cell transplant recipients, with an incidence rate of 5-15% and an associated mortality of 30-60%. It remains unclear why certain patients develop invasive aspergillosis while others, undergoing identical transplant regimen and similar post transplant immunosuppression,
Lamoth Frédéric +2 more
openaire +3 more sources
Therapeutic effects of Rheumatoid Arthritis on Aspergillosis development [PDF]
Aspergillosis is a common fungal infection with systemic characteristics, which is caused by various species of Aspergillus. The infection could develop in immunocompromised and immunocompetent patients under specific circumstances. Based on the clinical
Ali AL-Janabi
doaj +1 more source
Aspergillosis in Chronic Granulomatous Disease
Patients with chronic granulomatous disease (CGD) have the highest life-time incidence of invasive aspergillosis and despite the availability of antifungal prophylaxis, infections by Aspergillus species remain the single most common infectious cause of ...
Jill King +2 more
doaj +1 more source
Performance of serum biomarkers for the early detection of invasive aspergillosis in febrile, neutropenic patients: a multi-state model. [PDF]
The performance of serum biomarkers for the early detection of invasive aspergillosis expectedly depends on the timing of test results relative to the empirical administration of antifungal therapy during neutropenia, although a dynamic evaluation ...
Michaël Schwarzinger +5 more
doaj +1 more source

