Results 71 to 80 of about 27,772 (222)

Evidence-based clinical standard for the diagnosis and treatment of invasive lung aspergillosis in the patient with oncohematologic disease

Brazilian Journal of Infectious Diseases
Aspergillosis is a disease caused by the filamentous fungus Aspergillus spp. with a spectrum of clinical presentation that includes invasive and noninvasive forms.
Jorge Alberto Cortés, Diego Andrés Rodríguez-Lugo, Martha Carolina Valderrama-Rios, Ricardo Rabagliati, Domenico Capone, Carlos Arturo Álvarez-Moreno, Fabio Varón-Vega, Laura Cristina Nocua-Báez, Cándida Diaz-Brochero, Leonardo Enciso Olivera, Sonia Isabel Cuervo-Maldonado, Luis Thompson, Dora E. Corzo-León, Luis E. Cuéllar, Erika Paola Vergara, Fernando Riera, Patricia Cornejo-Juárez, Rita Rojas, Beatriz L. Gómez, Adriana Marcela Celis-Ramírez, José Luis Sandoval-Gutiérrez, Mauricio Sarmiento, Diana Lorena Ochoa, Marcio Nucci   +23 more
doaj   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6584-6594, August 2026.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Treatment of Infections Due to Aspergillus terreus Species Complex

Journal of Fungi, 2018
The Aspergillus terreus species complex is found in a wide variety of habitats, and the spectrum of diseases caused covers allergic bronchopulmonary aspergillosis, Aspergillus bronchitis and/or tracheobronchitis, and invasive and disseminated ...
Cornelia Lass-Flörl
doaj   +1 more source

Primary Invasive Intestinal Aspergillosis in a Non-Severely Immunocompromised Patient [PDF]

Korean Journal of Critical Care Medicine, 2016
Invasive aspergillosis (IA) is most commonly seen in patients with risk factors, such as cytotoxic chemotherapy, prolonged neutropenia, corticosteroids, transplantation and acquired immune deficiency syndrome. IA commonly occurs in the respiratory tract.
Eunmi Gil, Tae Sun Ha, Gee Young Suh, Chi Ryang Chung, Chi-Min Park   +4 more
doaj   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Isavuconazole for the treatment of invasive aspergillosis and mucormycosis: current evidence, safety, efficacy, and clinical recommendations [PDF]

, 2016
Suganthini Krishnan Natesan,1,2 Pranatharthi H Chandrasekar1 1Division of Infectious Diseases, Department of Internal Medicine, Wayne State University, 2John D Dingell VA Medical Center, Detroit, MI, USA Abstract: The majority of invasive mold infections
Chandrasekar PH, Natesan SK
core  

Inflammation‐driven variability in drug metabolism: Insights from voriconazole treatment of HSCT recipients

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2250-2259, July 2026.
Aims Voriconazole is commonly used to prevent fungal infections after haematopoietic stem cell transplantation (HSCT). Although its metabolism is influenced by CYP2C19 genetics and inflammation, their combined effect is rarely considered in clinical practice, and integrated analyses remain limited.
Sylvia D. Klomp, Martijn L. Manson, Henk‐Jan Guchelaar, Stefan Böhringer, Esther H. M. van Egmond, Peter A. von dem Borne, Jesse J. Swen   +6 more
wiley   +1 more source

Invasive pulmonary aspergillosis in an immunocompetent patient [PDF]

, 2011
Aspergillosis is the group of diseases caused by the Aspergillus species, which cause a broad spectrum of disease, ranging from hypersensitivity reactions to direct angioinvasion.
Iliana Samara Hurtado Rendon, Hurtado Rendon, Iliana Samara, Ciubotaru, Ronald L., Pathak, Vikas, Vikas Pathak, Ronald L. Ciubotaru   +5 more
core   +1 more source

[Azole-resistant invasive aspergillosis] [PDF]

, 2009
Invasive aspergillosis caused by medical triazole-resistant Aspergillus fumigatus is described in two patients. A 31-year-old male with chronic granulomatous disease developed pulmonary aspergillosis despite itraconazole prophylaxis. A.
Warris, A., Melchers, W.J.G., Bresters, D., Meer, J.W.M. van der, Linden, J.W.M. van der, Verweij, P.E.   +5 more
core   +2 more sources

Disseminated cerebral aspergillosis complicated by thrombotic microangiopathy

Medical Mycology Case Reports, 2019
Invasive aspergillosis (IA) is a serious condition that can affect almost any organ. Cerebral aspergillosis itself is rapidly fatal without treatment. We report a case of disseminated cerebral IA in a patient exposed to cyclophosphamide, rituximab and ...
Robynn Lester, Deirdre Church, Anshula Ambasta   +2 more
doaj   +1 more source