Results 71 to 80 of about 83,754 (257)

Coexistence of invasive ductal breast carcinoma and fibroadenoma

The Pan African Medical Journal, 2019
Fibroadenomas are the most common breast disease that occurs usually in young. The coexistence of an invasive ductal carcinoma and a fibroadenoma in the ipsilateral breast is extremely rare. We present the case of a 52 years woman, presented to us for an
Fatma Saadallah, Imen Bouraoui, Lamia Naija, Saida Sakhri, Ines Zemni, Jamel Ben Hassouna, Tarak Ben Dhieb, Hatem Bouzaiene, Khaled Rahal   +7 more
doaj   +1 more source

Development of immunocompetent models for primary and metastatic ER+ breast cancer

Animal Models and Experimental Medicine, EarlyView.
This study explores syngeneic, immunocompetent models of ER+ breast cancer in 129S6/SvEv mice, using trackable tumor cells to model both primary tumors and metastasis. The models show promise, while also revealing limitations for studying advanced disease and immune interactions.
Devon M. Bull, Jody Hazlett, Emily Schulpen, Sophie Tunnicliffe, Alexander D. McLellan, Anita K. Dunbier   +5 more
wiley   +1 more source

Gallbladder metastasis in invasive ductal breast cancer with concurrent gallstones and gallbladder carcinoma

Discover Oncology
The gallbladder is an uncommon location for tumor metastases. Breast cancer seldom spreads to the gallbladder, although melanoma and renal cell tumors typically do.
Rujuan Wang, Feng Zhao, Tao Yan, Yongtian Li, Danqing Cheng, Wenping Wang, Chongyue Tian, Hao Yu   +7 more
doaj   +1 more source

Quantitative detection of JMJD3 and Ki-67 in invasive ductal carcinoma of breast and their relationship with molecular typing and clinicopathological features

Zhongguo aizheng zazhi, 2020
Background and purpose: The study of molecular markers for breast cancer is helpful to diagnosis of the disease and prediction of prognosis in breast cancer patients.
徐小艳, 王建君, 王　慧, 王　娜, 刘　薇, 杨金花   +5 more
doaj  

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Granulomatous reaction associated with breast carcinoma: A report of two cases

Saudi Journal of Medicine and Medical Sciences, 2014
The presence of a granulomatous reaction in association with a breast carcinoma is a rare phenomenon. We present two cases of breast carcinoma, invasive ductal and invasive lobular carcinoma in which a non-caseating granulomatous response was present ...
Timor Alalshee, Tahira Hamed, Sheikh M Shafi   +2 more
doaj   +1 more source

Gephyrin Neurological Autoimmunity

Annals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano, Friederike A. Arlt, Naomi Arenson, Irena Dujmovic Basuroski, Divyanshu Dubey, Connie E. Lesnick, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael A. Lane, Andrew McKeon   +10 more
wiley   +1 more source

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

British Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong, Luisa Rojas Chavarro, Paul Jones, David Egging, Wanchana Ungphakorn, Marta Valle, Ivan Matthews   +6 more
wiley   +1 more source

The Role of Interleukin-10 in Women with Metastatic Invasive Ductal Carcinoma

مجلة كلية الطب, 2011
Background: Breast cancer is the malignant tumor that forms from the uncontrolled growth of abnormal breast cells. It usually affects tissues involved in milk production (Ductal and lobular tissues).
Amina N. Althwani, Mohammed A. Najm
doaj   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source