Results 141 to 150 of about 74,757 (299)

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Polyhexanide based contact lens storage fluids frequently exhibit insufficient antifungal activity against Fusarium species

International Journal of Medical Microbiology
Purpose: Fusarium keratitis is a severe infection of the anterior eye, frequently leading to keratoplasty or surgical removal of the affected eye. A major risk factor for infection is the use of contact lenses.
Benedikt Schrenker, Anna Zimmermann, Thorsten Koch, Grit Walther, Ronny Martin, Daniel Kampik, Oliver Kurzai, Johanna Theuersbacher   +7 more
doaj   +1 more source

Incidence of unplanned gastrostomy tube replacements and associated complications in people with motor neurone disease and other conditions: A retrospective audit of an Australian dietitian‐led clinic

Nutrition in Clinical Practice, EarlyView.
Abstract Background Gastrostomy tube placement is a common intervention for long‐term nutrition in people with dysphagia. Minimising complications such as tube dislodgement is integral in gastrostomy management, as unplanned replacements may require urgent care to prevent stoma closure.
Emily Farrugia, Shanelle Bailey, Adam I. Semciw, Mani Suleiman, Mark Tacey, Caroline J. Tuck, Liam M. Hannan   +6 more
wiley   +1 more source

Ranavirus risk depends on host community characteristics more than the presence of Batrachochytrium dendrobatidis

Oikos, EarlyView.
Novel parasite introductions are threatening wildlife communities globally. The degree of threat depends on the ecological context, namely host community characteristics and the presence of other parasites. How these two factors interact to shape the outcomes of parasite introductions is not known. We experimentally investigated how infection following
David R. Daversa, Andy Fenton, Lola M. Brookes, Gonçalo M. Rosa, Chris Sergeant, Trenton W. J. Garner   +5 more
wiley   +1 more source

Human Fungal Infections: Diagnostic and Therapeutic Challenges [PDF]

Fungal infections, either invasive and disseminated or cutaneous and superficial, are an important and increasing cause of morbidity [...
Eleni Gavriilaki, Timoleon-Achilleas Vyzantiadis, Athanasios Tragiannidis   +2 more
core   +1 more source

Clinical Value of Metagenomic Next‐Generation Sequencing Versus Conventional Methods in Diagnosing Cryptococcal Infection After Kidney Transplantation

Organ Medicine, EarlyView.
This retrospective study evaluated metagenomic next‑generation sequencing (mNGS) against conventional methods (India ink, culture, antigen) for diagnosing cryptococcal infection in 16 kidney transplant recipients. mNGS showed a significantly higher positivity rate (93.8% vs 62.5%, p = 0.031) and shorter turnaround time (24 vs. 120 h, p < 0.001).
Luhao Liu, Rongxin Chen, Haonan Lin, Yuhe Guo, Guanghui Li, Jiali Fang, Zheng Chen   +6 more
wiley   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Respiratory profile of pediatric patients undergoing hematopoietic stem cell transplantation studied by oscillometry – A TRANSPIRE cohort

Pediatric Investigation, EarlyView.
These are results from a multi‐center collaboration between four large pediatric institutions, investigating baseline respiratory system function in a cohort of children undergoing hematopoietic stem cell transplantation. This manuscript proposes respiratory oscillometry as a novel way to prospectively follow lung function in these children.
Maureen B. Parenti, Julian Allen, Lisa R. Young, Heather Boas, Jason Freedman, Christopher Towe, Jane Koo, Kasiani Myers, Jason C. Woods, Adam Lane, Jonathan Gaffin, Wai Wong, Leslie Lehmann, Fernando Urrego, Gabriel Salinas Cisneros, Matthew F. Abts, K. Scott Baker, Manuel Silva‐Carmona, Erin Doherty, Paul D. Robinson, Margaret MacMillan, Stella M. Davies, Samuel B. Goldfarb   +22 more
wiley   +1 more source

Conservation status of species used in the UK herbal medicine industry

PLANTS, PEOPLE, PLANET, EarlyView.
Given the ongoing biodiversity crisis, sustainable use and management of medicinal plants is critical. We assessed the conservation status, threats and conservation actions of 298 species sold by UK suppliers to medical herbalists. We found that most species used are unevaluated, representing a gap in conservation knowledge, and of those with ...
Isabella Flowers, Jon C. Lovett, Christopher Hassall   +2 more
wiley   +1 more source

Epistemic diversity and the politics of knowledge in plant disease management: Insights from the Xylella fastidiosa epidemic in southern Italy

PLANTS, PEOPLE, PLANET, EarlyView.
Xylella fastidiosa is a major plant pathogen affecting crops such as grapes, citrus, almonds, and olives, with potentially severe consequences for agricultural production and rural livelihoods worldwide. This paper examines the conflict around the management of the X. fastidiosa outbreak affecting olive trees in southern Italy.
Fabio Gatti, David Ludwig, Phil Macnaghten   +2 more
wiley   +1 more source