Results 51 to 60 of about 577,114 (263)

Avaliação da Dispersão de Sementes de Pinus taeda L. pela Análise dos Anéis de Crescimento de Árvores de Regeneração Natural

open access: yesFloresta e Ambiente
RESUMO As árvores de Pinus taeda – introduzidas no Brasil em 1880 e em ensaios experimentais em 1936 – têm sido relacionadas na literatura especializada ao processo de invasão biológica de algumas áreas de campos gerais e de altitude dos estados do ...
Mario Tomazello Filho   +9 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Predictors of Invasiveness in Adenocarcinoma of Lung with Lepidic Growth Pattern

open access: yesMedical Sciences, 2022
Lung adenocarcinoma with lepidic growth pattern (LPA) is characterized by tumor cell proliferation along intact alveolar walls, and further classified as adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA) and invasive lepidic ...
Timothy J. Young   +10 more
doaj   +1 more source

The role of acidity in solid tumour growth and invasion [PDF]

open access: yesJournal of Theoretical Biology, 2005
Acidic pH is a common characteristic of human tumours. It has a significant impact on tumour progression and response to therapies. In this paper, we develop a simple model of three-dimensional tumour growth to examine the role of acidosis in the interaction between normal and tumour cell populations.
Smallbone, K   +3 more
openaire   +5 more sources

FOSL1 promotes tumor growth and invasion in ameloblastoma

open access: yesFrontiers in Oncology, 2022
BackgroundFOSL1, a key component of the Activating protein-1 (AP-1) transcriptional complex, plays an important role in cancer cell migration, invasion, and proliferation. However, the impact of FOSL1 in ameloblastoma (AM) has not been clarified. Herein, we aimed to assess the expression of FOSL1 and investigate its functional role in AM.MethodsThe ...
Gan Xiong   +27 more
openaire   +3 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The rapid evolution of an invasive plant due to increased selection pressures throughout its invasive history

open access: yesEcotoxicology and Environmental Safety, 2022
Invasive plants are highly successful because they can quickly adapt to selection pressures imposed by both biotic and abiotic stressors. Since selection pressures may vary across temporal and biogeographical gradients, the growth and fitness of invasive
Wenheng Gong   +7 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

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