Results 111 to 120 of about 156,339 (303)

Identification of Exhaled Volatile Organic Compounds Biomarkers for Lung Cancer Under Data‐Limited Conditions Using Data Augmentation and Multi‐View Feature Selection

Advanced Intelligent Discovery, EarlyView.
This work introduces a novel framework for identifying non‐small cell lung cancer biomarkers from hundreds of volatile organic compounds in breath, analyzed via gas chromatography‐mass spectrometry. This method integrates generative data augmentation and multi‐view feature selection, providing a stable and accurate solution for biomarker discovery in ...
Guancheng Ren, Bohao Liu, Zhiyuan Qu, Xue Jiang, Heng Zhao, Danyao Qu, Ruizhi Ning, Chen Su, Taoping Liu, Guangjian Zhang, Weiwei Wu   +10 more
wiley   +1 more source

Machine Learning‐Driven Digital Twin of a Field‐Effect Transistor‐Based Hormone Biosensor for Real‐Time Estradiol Monitoring

Advanced Intelligent Systems, EarlyView.
A machine learning‐driven digital twin simulates an aptamer‐functionalized BioFET measuring 17β‐estradiol. Real‐time Isd signals are processed, features are extracted, and trained models estimate hormone concentration. In parallel, a one‐step‐ahead forward model learns biosensor dynamics and generates realistic synthetic signals, enabling in silico ...
Anastasiia Gorelova, Alexandra Parichenko, Shirong Huang, Santiago Melia, Gianaurelio Cuniberti   +4 more
wiley   +1 more source

Cytosolic Phosphoenoylpyruvate Carboxykinase Deficiency: Clinical, Biochemical, and Genetic Features of Five Non‐Finnish Patients

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt, Polona Le Quesne Stabej, Claire Hart, Mark De Hora, Sarah Hulley, Mark Anderson, Harry G. Leitch, Hugh Lemonde, Bryony Ryder, James Davison   +9 more
wiley   +1 more source

Approach to mechanical ventilation: a simplified approach for a pulmonologist

Monaldi Archives for Chest Disease
Mechanical ventilation is a critical intervention for patients with respiratory failure, providing essential support for oxygenation and ventilation while reducing the work of breathing. It operates through key breath-phase variables: triggering (breath
Pratap Upadhya, Sanjana H S, Harshith R, Vemuri Mahesh Babu, Karthik Balasoupramaniane, Zeenathaalam Nadaf   +5 more
doaj   +1 more source

Isovolumic relaxation strain imaging is an accurate and sensitive approach for detection of active diastolic dysfunction: A preclinical study

Animal Models and Experimental Medicine, EarlyView.
A modified approach was developed to accurately identify the isovolumetric relaxation time (IVRT) using an apical three‐chamber view. Compared with conventional echocardiography, isovolumic relaxation strain imaging (IVSI) helps to detect the earlier alternations of diastolic function in transverse aortic constriction (TAC) mice.
Jingjing Liang, Juncheng Wang, Jun Cheng, Yanggan Wang   +3 more
wiley   +1 more source

Effectiveness of non-invasive mechanical ventilation in patients with acute respiratory failure

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2018
Background: the predictive factors of success of non-invasive mechanical ventilation in patients with acute respiratory failure are important to define their progress.Objective: to determine the effectiveness of non-invasive mechanical ventilation ...
Gilberto Lázaro Betancourt-Reyes
doaj  

Acute kidney injury in patients with invasive mechanical ventilation in Guantanamo, 2018-2019

Revista Información Científica, 2020
Introduction: acute kidney injury is a very common complication in the intensive care units, especially in patients with invasive mechanical ventilation. Objective: to characterize acute kidney damage in patients with invasive mechanical ventilation in
Marisela de León-Vidal, José Alfredo Estevan-Soto, Eglhys Granado-Couceiro, Leonardo Fernández-Fernández, Dayana Rodríguez-Reyes   +4 more
doaj  

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

Impact of vaccination and SARS-CoV-2 variants on severe COVID-19 outcomes: a cross-sectional study, Brazil, 2021-2022

Epidemiologia e Serviços de Saúde
Objective To investigate association between vaccination, SARS-CoV-2 variants, and severe outcomes among Brazilian patients hospitalized due to COVID-19.
Luiza Paiva Moraes, Letícia Martins Raposo   +1 more
doaj   +2 more sources

Predictors and outcome of invasive mechanical ventilation in hospitalized patients with sepsis: data from National Inpatient Sample

Journal of Community Hospital Internal Medicine Perspectives, 2018
Background: Sepsis is a significant cause of mechanical ventilation in hospitalized patients. Objective: The aim of our study was to recognize the demographic and clinical characteristics associated with an increased need for invasive mechanical ...
Rashmi Dhital, Sijan Basnet, Dilli Ram Poudel   +2 more
doaj   +1 more source