Results 101 to 110 of about 3,508,285 (256)

Refining OVCAR‐3 xenograft models of peritoneal carcinomatosis in nu/nu mice: Comparative intraperitoneal implantation strategies and the role of basement membrane matrix

Animal Models and Experimental Medicine, EarlyView.
A refined murine model of advanced ovarian cancer was established by comparing localized preperitoneal implantation and intraperitoneal injection of OVCAR‐3Luc cells. While localized implantation showed limited tumor persistence, intraperitoneal delivery with BME produced sustained diffuse dissemination confirmed by BLI and histology, providing a ...
M. Teresa Perelló‐Trias, Antonio Jose Serrano‐Muñoz, Juan J. Segura‐Sampedro, Adriana M. Quintero‐Duarte, Joana M. Ramis, Marta Monjo   +5 more
wiley   +1 more source

Respiratory care year in review 2010: part 2. Invasive mechanical ventilation, noninvasive ventilation, pediatric mechanical ventilation, aerosol therapy

, 2011
The purpose of this paper is to review the recent literature related to invasive mechanical ventilation, NIV, pediatric mechanical ventilation, and aerosol therapy. Topics covered related to invasive mechanical ventilation topics include the role of PEEP
Diblasi RM, Restrepo RD, Hess DR, Macintyre NR, NAVA, STEFANO, Neil R MacIntyre, Robert M DiBlasi, Ruben D Restrepo, Stefano Nava, Dean R Hess   +9 more
core   +1 more source

Developing a strain‐dependent susceptibility to hepatocellular carcinoma in a murine model based on histopathological evidence and genetic context

Animal Models and Experimental Medicine, EarlyView.
Using F1 (C57BL/6J/Smad4+/− X CC) mice, we found that partial loss of Smad4 promotes liver carcinogenesis in a strain‐dependent manner, highlighting the importance of genetic modifiers in tumor susceptibility. The use of Collaborative Cross mice provides a valuable platform for uncovering genotype‐specific cancer susceptibilities in preclinical ...
Osayd Zohud, Aysar Nashef, Imad Abu‐Elnaaj, Fuad A. Iraqi   +3 more
wiley   +1 more source

Association between respiratory distress time and invasive mechanical ventilation in COVID-19 patients: A multicentre regional cohort study

Pulmonology
Aim To determine whether the duration of respiratory distress symptoms in severe COVID-19 pneumonia affects the need for invasive mechanical ventilation and clinical outcomes.Materials and methods An observational multicentre cohort study of patients ...
S. Busani, I. Coloretti, M. Baciarello, V. Bellini, M. Sarti, E. Biagioni, R. Tonelli, A. Marchioni, E. Clini, G. Guaraldi, C. Mussini, M. Meschiari, T. Tonetti, L. Pisani, S. Nava, E. Bignami, M.V. Ranieri, M. Girardis   +17 more
doaj   +1 more source

Baseline characteristics of patients in relation to the frequency of the need for invasive mechanical ventilation.

, 2018
Baseline characteristics of patients in relation to the frequency of the need for invasive mechanical ventilation.
Fei Teng (201085), Tianjiao Xue (5801870), Huan Ye (1793494)   +2 more
core   +1 more source

Rate and Shape of Functional Decline in Amyotrophic Lateral Sclerosis Identify Clinically Distinct Amyotrophic Lateral Sclerosis Phenotypes

Annals of Neurology, EarlyView.
Objective The ALS Functional Rating Scale–Revised decline rate compresses trajectory shape into a single number, potentially missing distinct phenotypes. We tested whether shape identifies phenotypes that rate does not distinguish, and whether post‐hoc analysis recovers a hidden ultrarapid subgroup. Methods From the Piemonte and Valle d'Aosta register (
Andrea Calvo, Cristina Moglia, Antonio Canosa, Umberto Manera, Elisabetta Zucchi, Giulia Gianferrari, Ilaria Martinelli, Gabriele Mora, Sara Cabras, Francesca Palumbo, Enrico Matteoni, Giorgio Pellegrino, Emilio Minerva, Daniela Pascariu, Stefano Callegaro, Fabrizio D'Ovidio, Rosario Vasta, Letizia Mazzini, Fabiola De Marchi, Jessica Mandrioli, Adriano Chiò   +20 more
wiley   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

Animal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang, Fang‐Fang Guo, Wen‐Juan Du, Meng Li, Aftab Shaukat, Zhu‐Qing Jia, Shu‐Cheng Huang   +6 more
wiley   +1 more source

HOME NON-INVASIVE MECHANICAL VENTILATION THERAPY IN ELDERLY COPD PATIENTS

, 2015
Introduction: Home non-invasive mechanical ventilation has been widely used in recent years as a treatment for chronic obstructive pulmonary disease in patients with chronic hypercapnic respiratory failure. We aimed to evaluate the use of home mechanical
SEVİNÇ, CAN, Turan, Onur
core   +1 more source

Non-invasive ventilation of the preterm infant

, 2008
Non-invasive ventilation (NIV) is increasingly being used in preterm infants with the purpose of reducing the risk of adverse pulmonary outcome associated with invasive mechanical ventilation.
Claure, Nelson, Bancalari, Eduardo, Nelson Claure, Eduardo Bancalari   +3 more
core   +1 more source