Results 101 to 110 of about 3,338,677 (297)

Development and validation of a risk model for identification of non-neutropenic, critically ill adult patients at high risk of invasive Candida infection: the Fungal Infection Risk Evaluation (FIRE) Study. [PDF]

open access: yes, 2013
BACKGROUND: There is increasing evidence that invasive fungal disease (IFD) is more likely to occur in non-neutropenic patients in critical care units.
Dybowski, R   +29 more
core   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

open access: yesAdvanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai   +18 more
wiley   +1 more source

Anion–π Interaction‐Regulated Ion Generation and High Piezoionic Response in Ultrasoft Low‐Salinity Hydrogels

open access: yesAngewandte Chemie, EarlyView.
The first hydrogel system employing anion–π interactions as a central design motif is developed. The cooperative aromatic–phosphate interaction motif provides dynamic cohesion and is proposed to regulate the separation and transport of water‐derived ionic species, achieving high piezoionic response in injectable, self‐healing, ultrasoft, low‐salinity ...
Jinyang Jiang   +11 more
wiley   +2 more sources

Analysis of factors affecting long-term quality of life in children on home mechanical ventilation: a 4-year prospective observational cohort study

open access: yesItalian Journal of Pediatrics
Background Home mechanical ventilation improves survival of critically ill children but partially affects quality of life. Studies in China have more often analyzed the risk factors for death from prolonged mechanical ventilation in hospitalized children
Yingying Zhang   +8 more
doaj   +1 more source

History of Intermittent Mandatory Ventilation 1971 to present. Part two

open access: yes, 2022
Medical history is often overlooked as advances keep moving forward. Seldom is it that advances in medicine are truly new, unique ideas, but rather built on ideas that have been considered before.
Ronald R. Sanderson   +3 more
core   +1 more source

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

open access: yesAdvanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury   +18 more
wiley   +1 more source

Qualitative study on MDT team cooperation in early activities of patients with invasive mechanical ventilation in ICU

open access: yesHuli yanjiu, 2021
ObjectiveTo understand and summarize the cooperation methods,existing problems and implementation obstacles of the early activities of ICU patients with invasive mechanical ventilation under the multi⁃disciplinary treatment(MDT) team model,and to provide
WANG Xueqin, ZHANG Chuanlin, MI Jie
doaj  

Mean airway pressure - Minute ventilation product (mM): A simple and universal surrogate equation to calculate mechanical power in both volume and pressure controlled ventilation

open access: yes
Introduction Mechanical power represents the energy delivered by a mechanical ventilator onto the lungs. It incorporates all the variables participating in ventilator-induced lung injury, including driving pressure, tidal volume, positive end expiratory
Claudio L. Franck   +3 more
core   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

High-flow Oxygen and Nitric Oxide inhalation versus high-flow oxygen alone to prevent intubation in hypoxaemic Respiratory failure (HONOR): a pilot randomised controlled trial protocol

open access: yesPilot and Feasibility Studies
Background When conventional oxygen therapies fail, endotracheal intubation and invasive mechanical ventilation are the current standard of care in patients with acute hypoxaemic respiratory failure. However, invasive mechanical ventilation is associated
Luke Churchill   +4 more
doaj   +1 more source

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