Results 21 to 30 of about 8,385 (178)

Neisseria meningitidis IgA1-specific serine protease exhibits novel cleavage activity against IgG3

Virulence, 2021
Neisseria meningitidis (meningococcus) is a common bacterial colonizer of the human nasopharynx but can occasionally cause very severe systemic infections with rapid onset.
Christian Spoerry, Jens Karlsson, Marie-Stephanie Aschtgen, Edmund Loh   +3 more
doaj   +1 more source

A case of invasive meningococcal disease presenting as myopericarditis

Clinical Infection in Practice, 2021
Background: Neisseria meningitidis is a universally-feared Gram negative diplococcus, and infection confers high rates of morbidity and mortality despite effective antimicrobial therapy.
Simon M. Durkin, Clemency Britton, Graham S. Cooke, Ravi Mehta   +3 more
doaj   +1 more source

Evidence for Multi-Organ Infection During Experimental Meningococcal Sepsis due to ST-11 Isolates in Human Transferrin-Transgenic Mice

Microorganisms, 2020
The description of invasive meningococcal disease that is provoked by Neisseria meningitidis (Nm) is frequently restricted to meningitis. However, a wide panel of clinical presentations can be encountered including severe forms with intense inflammatory ...
Michael Levy, Myriam Aouiti Trabelsi, Muhamed-Kheir Taha   +2 more
doaj   +1 more source

Control of invasive meningococcal disease

International Journal of Evidence-Based Healthcare, 2016
Neisseria meningitidis still leads to deaths and severe disability in children, adolescents and adults. Six different capsular groups of N. meningitidis cause invasive meningococcal disease in the form of meningitis and septicaemia in humans. Although conjugate meningococcal vaccines have been developed to provide protection against four of the ...
Marshall, H, Wang, B, Wesselingh, S, Snape, M, Pollard, A   +4 more
openaire   +3 more sources

Primary meningococcal arthritis in a COVID-19 18-year-old man: a case report and review of the literature

BMC Infectious Diseases, 2021
Background SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection is associated with various complications. PMA (primary meningococcal arthritis) is a rare meningococcus-associated disease causing arthritis of the knee usually, without ...
Norman Ducatez, Marine Chancel, Youcef Douadi, Charles Dayen, Rémi Suguenot, Emmanuelle Lecuyer, Benoit Brihaye, Houcine Bentayeb   +7 more
doaj   +1 more source

Impact of Meningococcal B Vaccine on Invasive Meningococcal Disease in Adolescents

Clinical Infectious Diseases, 2021
Abstract Background From 2017, a statewide cluster randomized trial was conducted in South Australia to assess the impact of the meningococcal B vaccine 4CMenB on pharyngeal Neisseria meningitidis carriage in adolescents.
Mark McMillan, Bing Wang, Ann P Koehler, Thomas R Sullivan, Helen S Marshall   +4 more
openaire   +2 more sources

Evaluating the effectiveness of the 4CMenB vaccine against invasive meningococcal disease and gonorrhoea in an infant, child and adolescent program: protocol

Human Vaccines & Immunotherapeutics, 2021
Invasive meningococcal disease causes significant morbidity and mortality worldwide, with serogroup B being one of the predominant serogroups in Australia for many years.
Helen S. Marshall, Prabha H. Andraweera, Bing Wang, Mark McMillan, Ann P. Koehler, Noel Lally, Sara Almond, Emma Denehy, Michele A’Houre, Lynne C. Giles, Louise Flood   +10 more
doaj   +1 more source

Second hand smoke exposure and the risk of invasive meningococcal disease in children: systematic review and meta-analysis

BMC Public Health, 2012
Background Invasive meningococcal disease remains an important cause of serious morbidity and mortality in children and young people. There is a growing body of literature to suggest that exposure to passive smoke may play a role in the development of ...
Murray Rachael L, Britton John, Leonardi-Bee Jo   +2 more
doaj   +1 more source

Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides

Angewandte Chemie, EarlyView.
Well‐defined α(2,8)‐ and α(2,9)‐linked oligosialic acids of different lengths can be prepared by employing recombinant bacterial polysialyltransferases in combination with chemically modified CMP‐Neu5Ac derivatives. After transfer, a sialoside is formed bearing an artificial entity, which blocks further glycosylation.
Jelle A. Fok, Keshav Kishor, Mehman I. Bunyatov, Gerlof P. Bosman, Geert‐Jan Boons   +4 more
wiley   +2 more sources

Expanding prevention of invasive meningococcal disease

Expert Review of Vaccines, 2009
Invasive meningococcal disease due to serogroups A, C, Y and W-135 is a serious, vaccine-preventable, worldwide public-health problem. Despite early treatment and advances in medical care, morbidity and mortality rates have essentially remained unchanged.
Stephen I, Pelton, Gregory P, Gilmet
openaire   +2 more sources