Results 41 to 50 of about 8,385 (178)

Invasive Meningococcal Disease in Adolescents and Young Adults [PDF]

JAMA, 2001
Incidence of invasive meningococcal disease has increased recently in persons aged 15 through 24 years.To characterize meningococcal infection in adolescents and young adults in Maryland during the 1990s.Population-based surveillance study for meningococcal disease from January 1, 1990, through December 31, 1999, in Maryland.Maryland residents ...
L H, Harrison, M A, Pass, A B, Mendelsohn, M, Egri, N E, Rosenstein, A, Bustamante, J, Razeq, J C, Roche   +7 more
openaire   +2 more sources

UKMenCar4: A cross-sectional survey of asymptomatic meningococcal carriage amongst UK adolescents at a period of low invasive meningococcal disease incidence [version 2; peer review: 2 approved]

Wellcome Open Research, 2019
Carriage of Neisseria meningitidis, the meningococcus, is a prerequisite for invasive meningococcal disease (IMD), a potentially devastating infection that disproportionately afflicts infants and children.
Holly B. Bratcher, Charlene M. C. Rodrigues, Adam Finn, Mandy Wootton, J. Claire Cameron, Andrew Smith, Paul Heath, Shamez Ladhani, Matthew D. Snape, Andrew J. Pollard, Richard Cunningham, Raymond Borrow, Caroline Trotter, Stephen J. Gray, Martin C. J. Maiden, Jenny M. MacLennan   +15 more
doaj   +1 more source

Insights on Population Structure and Within-Host Genetic Changes among Meningococcal Carriage Isolates from U.S. Universities

mSphere, 2020
In 2015 and 2016, meningococcal carriage evaluations were conducted at two universities in the United States following mass vaccination campaigns in response to Neisseria meningitidis serogroup B (NmB) disease outbreaks.
Sandeep J. Joseph, Nadav Topaz, How-Yi Chang, Melissa J. Whaley, Jeni T. Vuong, Alexander Chen, Fang Hu, Susanna E. Schmink, Laurel T. Jenkins, Lorraine D. Rodriguez-Rivera, Jennifer D. Thomas, Anna M. Acosta, Lucy McNamara, Heidi M. Soeters, Sarah Mbaeyi, Xin Wang   +15 more
doaj   +1 more source

Meningococcemia in a vaccinated child receiving eculizumab and review of the literature

The Turkish Journal of Pediatrics, 2023
Background. Atypical hemolytic uremic syndrome (aHUS) is a rare and severe disease characterized by uncontrolled activation and dysregulation of the alternative complement pathway and development of thrombotic microangiopathy. Eculizumab, which is
Diana Üçkardeş, Nilüfer Göknar, Nurhan Kasap, Emre Keleşoğlu, Mustafa Arga, Cengiz Candan   +5 more
doaj   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Invasive meningococcal disease in Navarra in the era of a meningococcal C vaccine

Anales de Pediatría (English Edition), 2017
Systematic childhood vaccination against meningococcus C has had a considerable impact on meningococcal invasive disease (MID). The aim of this study is to perform an analysis on the epidemiology, the clinical features, and the factors associated with a worse prognosis of MID, in the era of a meningococcal C vaccine.The study included confirmed cases ...
Desirée, Morales, Laura, Moreno, Mercedes, Herranz, Enrique, Bernaola, Iván, Martínez-Baz, Jesús, Castilla   +5 more
openaire   +2 more sources

Whole genome analysis of Neisseria meningitidis isolates from invasive meningococcal disease collected in the Czech Republic over 28 years (1993-2020).

PLoS ONE, 2023
Invasive meningococcal disease belongs among the most dangerous infectious diseases in the world. Several polysaccharide conjugate vaccines against serogroups A, C, W and Y are available and two recombinant peptide vaccines against serogroup B (MenB ...
Michal Honskus, Pavla Krizova, Zuzana Okonji, Martin Musilek, Jana Kozakova   +4 more
doaj   +1 more source

A Decade of Invasive Meningococcal Disease Surveillance in Poland

PLoS ONE, 2013
Neisseria meningitidis is a leading etiologic agent of severe invasive disease. The objective of the study was to characterise invasive meningococcal disease (IMD) epidemiology in Poland during the last decade, based on laboratory confirmed cases.The study encompassed all invasive meningococci collected between 2002 and 2011 in the National Reference ...
Skoczyńska, Anna, Waśko, Izabela, Kuch, Alicja, Kadłubowski, Marcin, Gołębiewska, Agnieszka, Foryś, Małgorzata, Markowska, Marlena, Ronkiewicz, Patrycja, Wasiak, Katarzyna, Kozińska, Aleksandra, Matynia, Bożena, Hryniewicz, Waleria, And Particpants Of A Laboratory-Based Surveillanc, , ......... Et Al., ....., Jaworowska, Jadwiga   +14 more
openaire   +4 more sources

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source