Results 61 to 70 of about 10,113 (218)

Invasive meningococcal disease in Navarra in the era of a meningococcal C vaccine

Anales de Pediatría (English Edition), 2017
Systematic childhood vaccination against meningococcus C has had a considerable impact on meningococcal invasive disease (MID). The aim of this study is to perform an analysis on the epidemiology, the clinical features, and the factors associated with a worse prognosis of MID, in the era of a meningococcal C vaccine.The study included confirmed cases ...
Desirée, Morales, Laura, Moreno, Mercedes, Herranz, Enrique, Bernaola, Iván, Martínez-Baz, Jesús, Castilla   +5 more
openaire   +2 more sources

Whole genome analysis of Neisseria meningitidis isolates from invasive meningococcal disease collected in the Czech Republic over 28 years (1993-2020).

PLoS ONE, 2023
Invasive meningococcal disease belongs among the most dangerous infectious diseases in the world. Several polysaccharide conjugate vaccines against serogroups A, C, W and Y are available and two recombinant peptide vaccines against serogroup B (MenB ...
Michal Honskus, Pavla Krizova, Zuzana Okonji, Martin Musilek, Jana Kozakova   +4 more
doaj   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

A Decade of Invasive Meningococcal Disease Surveillance in Poland

PLoS ONE, 2013
Neisseria meningitidis is a leading etiologic agent of severe invasive disease. The objective of the study was to characterise invasive meningococcal disease (IMD) epidemiology in Poland during the last decade, based on laboratory confirmed cases.The study encompassed all invasive meningococci collected between 2002 and 2011 in the National Reference ...
Skoczyńska, Anna, Waśko, Izabela, Kuch, Alicja, Kadłubowski, Marcin, Gołębiewska, Agnieszka, Foryś, Małgorzata, Markowska, Marlena, Ronkiewicz, Patrycja, Wasiak, Katarzyna, Kozińska, Aleksandra, Matynia, Bożena, Hryniewicz, Waleria, And Particpants Of A Laboratory-Based Surveillanc, , ......... Et Al., ....., Jaworowska, Jadwiga   +14 more
openaire   +4 more sources

Advancing tele‐physiology: A chest patch solution for continuous, non‐invasive remote monitoring in a hypoxic environment

Experimental Physiology, EarlyView.
Abstract Skin‐mounted sensors are thin, flexible and lightweight electronic devices that enable monitoring of multiple physiological parameters. The aim of this study was to provide pilot evidence for possible utilization of a sensorized patch for capturing the bodily response to hypoxia. The subsequent phases of the study comprised a case report and a
Danilo Bondi, Ferdinando Calcagno, Elisa Fioraso, Camillo Di Giulio, Federico Schena, Anna Pedrinolla   +5 more
wiley   +1 more source

Sampling methods to detect carriage of Neisseria meningitidis; literature review.

, 2009
OBJECTIVES: Studies of meningococcal carriage are important in understanding the epidemiology of meningococcal disease and the impact of vaccination programmes. However, microbiological sampling methods to determine pharyngeal carriage are not consistent
Stuart, James, Roberts, Jonathan, Greenwood, Brian   +2 more
core   +1 more source

Effect of C5a Receptor Antagonist on the Osteogenic Differentiation of Dental Pulp Stem Cells

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objective Complement component 5a (C5a) binding to its receptor (C5aR) can mediate pro‐inflammatory immune responses, which impairs osteogenic differentiation of dental pulp stem cells (DPSCs). The present study aimed to evaluate the regulatory effect of C5aR antagonist (W54011) on the osteogenic differentiation of DPSCs in an in vitro ...
Xiaohan Tan, Junlong Hu, Junhui Li, Zhuangying Chen, Xin Shi, Jie Liu, Mingyue Liu, Weiping Hu   +7 more
wiley   +1 more source

Shifting From Systemic to Precision‐Targeted Complement Therapies: Opportunities and Hurdles

European Journal of Immunology, Volume 56, Issue 6, June 2026.
Complement therapeutics have expanded considerably, but systemic inhibitors remain limited by infection risks, breakthrough events, and loss of physiological functions. Emerging targeted approaches aim for organ‐, tissue‐, or cell‐specific modulation of complement activity, potentially offering greater precision while reducing treatment burden and ...
Marco Mannes, Wioleta M. Zelek, Leendert A. Trouw   +2 more
wiley   +1 more source

Early diagnosis model for meningitis supports public health decision making.

, 2011
OBJECTIVE: To develop a predictive model for rapid differential diagnosis of meningitis and meningococcal septicaemia to support public health decisions on chemoprophylaxis for contacts.
Ejidokun, Oluwatoyin O, Meltzer, Margie, Neville Q. Verlander, Fraser, Graham, Meltzer, M, Oluwatoyin O. Ejidokun, Rehman, Yasmin, Verlander, Neville Q, Ninis, Nelly, Margie Meltzer, Nelly Ninis, Muir, Peter, Fraser, G, Verlander, NQ, Rehman, Y, Close, RM, James M. Stuart, Graham Fraser, Peter Muir, Muir, P, Stuart, James M, Stuart, JM, Rebecca M. Close, Yasmin Rehman, Close, Rebecca M, Ejidokun, OO   +25 more
core   +1 more source

Mass gatherings: a review of the scope for meningococcal vaccination in the Indian context

Human Vaccines & Immunotherapeutics, 2021
The risk of meningococcal transmission is increased with crowding and prolonged close proximity between people. There have been numerous invasive meningococcal disease (IMD) outbreaks associated with mass gatherings and other overcrowded situations ...
Anand P Dubey, Rashna Dass Hazarika, Veronique Abitbol, Shafi Kolhapure, Someya Agrawal   +4 more
doaj   +1 more source