Results 71 to 80 of about 5,422,838 (209)

Trained Immunity in Childhood Vaccination

Acta Paediatrica, EarlyView.
Trained immunity as an emerging concept in paediatric vaccinology. Trained immunity links vaccine stimuli through epigenetic and metabolic reprogramming to enhanced innate immune cell function, thereby strengthening protection against diverse pathogens while promoting adaptive immune responses through more efficient antigen presentation and co ...
ChenRongRong Cai, Lubnaa Hossenbaccus, Eva Kaufmann   +2 more
wiley   +1 more source

Risk and protective factors for meningococcal disease in adolescents: matched cohort study [PDF]

, 2006
Objective: To examine biological and social risk factors for meningococcal disease in adolescents. Design: Prospective, population based, matched cohort study with controls matched for age and sex in 1:1 matching.
Stuart, J.M., Kaczmarski, E., Tully, J., Coen, P.G., Klein, N., Peckham, C., Viner, R.M., Zambon, M., Booth, C., Booy, R.   +9 more
core  

Sampling methods to detect carriage of Neisseria meningitidis; literature review.

, 2009
OBJECTIVES: Studies of meningococcal carriage are important in understanding the epidemiology of meningococcal disease and the impact of vaccination programmes. However, microbiological sampling methods to determine pharyngeal carriage are not consistent
Stuart, James, Roberts, Jonathan, Greenwood, Brian   +2 more
core   +1 more source

Australian consensus recommendations for the management of increased meningococcal infection risk in adults with neurological diseases treated with complement inhibitors

Internal Medicine Journal, EarlyView.
Abstract Complement inhibitor therapy carries a risk of serious infections, including meningococcal disease. Here we provide evidence‐based recommendations and expert consensus for immunisation and prophylactic treatment of patients receiving, or planning to receive, complement inhibitors for neurological conditions in the Australian setting.
Katherine A. Buzzard, Michael Barnett, Heidi Beadnall, Mirasol Forcadela, Lesley‐Ann Hall, Victoria G. Hall, Todd Hardy, Danny Hsu, Paul Kinsella, Mastura Monif, Sudarshini Ramanathan, Stephen W. Reddel, Sean Riminton, Douglas F. Johnson   +13 more
wiley   +1 more source

Sequential and Concurrent C5 and Neonatal Fc Receptor Inhibition in Prolonged Myasthenic Crisis due to Advanced Invasive Thymoma‐Associated Myasthenia Gravis: A Case Report and Literature Review

Clinical and Experimental Neuroimmunology, Volume 17, Issue 4, November 2026.
ABSTRACT Thymoma‐associated myasthenia gravis (TAMG) is frequently refractory, particularly when complicated by myasthenic crisis in advanced invasive disease. Complement C5 inhibitors and neonatal Fc receptor (FcRn) inhibitors have expanded the treatment of acetylcholine receptor (AChR) antibody‐positive generalized myasthenia gravis; however, their ...
Yuta Kizuka, Yuriko Nakamura, Kensuke Okada, Yu Okubo, Kaoru Kaseda, Hirofumi Toyama, Keisuke Asakura, Atsuya Takeda, Jin Nakahara, Kei Ishizuchi   +9 more
wiley   +1 more source

Dynamic models of pneumococcal carriage and the impact of the Heptavalent Pneumococcal Conjugate Vaccine on invasive pneumococcal disease. [PDF]

, 2010
BACKGROUND: The 7-valent pneumococcal conjugate vaccine has been introduced in national immunisation programmes of most industrialised countries and recently in two African GAVI eligible countries (Rwanda and The Gambia). However the long term effects of
George, Robert, Robert George, Y.H. Choi, Miller, Elizabeth, Edmunds, John W., Elizabeth Miller, Melegaro, Alessia, Yoon Hong Choi, E. Miller, Choi, Yoon Hong, Gay, Nigel J, Edmunds, W John, Nigel J Gay, R. George, W John Edmunds, Alessia Melegaro, N.J. Gay, W.J. Edmunds, Gay, Nigel J., George Robert, Miller Elizabeth, Edmunds W John, Choi Yoon, Gay Nigel J, Melegaro Alessia   +24 more
core   +2 more sources

The association of meningococcal disease with influenza in the United States, 1989-2009. [PDF]

PLoS ONE, 2014
Prior influenza infection is a risk factor for invasive meningococcal disease. Quantifying the fraction of meningococcal disease attributable to influenza could improve understanding of viral-bacterial interaction and indicate additional health benefits ...
Jessica Hartman Jacobs, Cécile Viboud, Eric Tchetgen Tchetgen, Joel Schwartz, Claudia Steiner, Lone Simonsen, Marc Lipsitch   +6 more
doaj   +1 more source

Early diagnosis model for meningitis supports public health decision making.

, 2011
OBJECTIVE: To develop a predictive model for rapid differential diagnosis of meningitis and meningococcal septicaemia to support public health decisions on chemoprophylaxis for contacts.
Ejidokun, Oluwatoyin O, Meltzer, Margie, Neville Q. Verlander, Fraser, Graham, Meltzer, M, Oluwatoyin O. Ejidokun, Rehman, Yasmin, Verlander, Neville Q, Ninis, Nelly, Margie Meltzer, Nelly Ninis, Muir, Peter, Fraser, G, Verlander, NQ, Rehman, Y, Close, RM, James M. Stuart, Graham Fraser, Peter Muir, Muir, P, Stuart, James M, Stuart, JM, Rebecca M. Close, Yasmin Rehman, Close, Rebecca M, Ejidokun, OO   +25 more
core   +1 more source

Mass gatherings: a review of the scope for meningococcal vaccination in the Indian context

Human Vaccines & Immunotherapeutics, 2021
The risk of meningococcal transmission is increased with crowding and prolonged close proximity between people. There have been numerous invasive meningococcal disease (IMD) outbreaks associated with mass gatherings and other overcrowded situations ...
Anand P Dubey, Rashna Dass Hazarika, Veronique Abitbol, Shafi Kolhapure, Someya Agrawal   +4 more
doaj   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, Volume 2, Issue 3, September 2026.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source