Results 171 to 180 of about 44,581 (298)

Rare Case Report: Coexistence of Complete Hydatidiform Mole and Normal Fetus in a Twin Pregnancy

open access: yesInternational Journal of Women's Health
Ping Li, XiuPing Liu Obstetrics and Gynecology Department of the Hebei Medical University Third Hospital, Shijiazhuang, People’s Republic of ChinaCorrespondence: Ping Li, Obstetrics and Gynecology Department of the Hebei Medical University Third Hospital,
Li P, Liu X
doaj  

Versatile DNA Hydrogel‐Mediated Delivery of Ginsenoside‐Encapsulated Small Extracellular Vesicles to Boost Diabetic Wound Repair

open access: yesAdvanced Science, EarlyView.
This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing   +14 more
wiley   +1 more source

The Immune Microenvironment of the Hydatidiform Mole and Invasive Mole

open access: yesObstetrics and Gynecology Research, 2023
Yiqun Yang   +3 more
openaire   +1 more source

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

open access: yesAdvanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng   +13 more
wiley   +1 more source

Polyelectrolyte Design Principles for Electrophoretic Drug Delivery

open access: yesAdvanced Science, EarlyView.
Structure–property–function mapping of polyelectrolytes reveals how composition and nanoscale order control on‐demand electrophoretic drug transport. Charge density quantified under implant‐relevant conditions shows that encapsulation limits swelling, enabling high effective charge density.
Helena Saarela Unemo   +8 more
wiley   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

open access: yesAdvanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv   +8 more
wiley   +1 more source

An invasive mole with bilateral kidney metastases: A case report. [PDF]

open access: yesOncol Lett, 2015
Yao K   +5 more
europepmc   +1 more source

CRISPR/Cas13a: Compensatory Target Activation Mechanism

open access: yesAdvanced Science, EarlyView.
CRISPR/Cas13a‐CTAM as a novel compensatory target activation mechanism that enables synergistic activation of Cas13a via two independently editable short RNA effectors. This dual‐effector system maintains enzymatic activity comparable to traditional single‐effector while significantly enhancing flexibility, sensitivity, and application scope.
Bowen Jiang   +8 more
wiley   +1 more source

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