AARS2‐SIRT5‐Driven DLD K445 Lactylation Promotes Cuproptosis Resistance in Glioblastoma Stem Cells
Lactylation of DLD at K445 by AARS2 suppresses PDH complex activity and reduces DLAT lipoylation, thereby conferring cuproptosis resistance in glioblastoma stem cells. SIRT5‐mediated delactylation restores PDH function and enhances cuproptosis sensitivity.
Mingtian Ding +12 more
wiley +1 more source
Choriocarcinoma Histologically Mimicking Epithelioid Trophoblastic Tumor - A Diagnostic Pitfall in Gestational Trophoblastic Neoplasia. [PDF]
Harsono AB +4 more
europepmc +1 more source
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu +9 more
wiley +1 more source
Persistent Low-Level hCG After Gestational Trophoblastic Neoplasia Remission: Treatment-Free Probability Stratified by Early hCG Course. [PDF]
Ji M +7 more
europepmc +1 more source
A partial‐inner‐cladding optical fiber (PICOF) is developed to suppress photothermal artifacts in fluorescent fiber‐optic thermometry by isolating the sensing layer from regions prone to photothermal effects. This structural design strategy enables high‐fidelity operation at elevated excitation power, achieving high accuracy (maximum absolute error ...
Sijie Su +7 more
wiley +1 more source
Living Newborn Back-To-Back With a Complete Hydatidiform Mole: A Rare Twin Pregnancy Outcome. [PDF]
Abou Chakra R +5 more
europepmc +1 more source
SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition
The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang +9 more
wiley +1 more source
A Rare Case of a Molar Pregnancy Coexisting with a Live Foetus in a Patient with Prior Exposure to M-2 Tone in First Trimester in Eastern Uganda: A Case Report. [PDF]
Nteziyaremye J, Waiswa S.
europepmc +1 more source
Thyroid Hormone Levels and Its Co-relation With Human Chorionic Gonadotropin in Patients With Molar Pregnancy. [PDF]
Singh P +5 more
europepmc +1 more source
Impact of different EMA/CO treatment regimens in women with gestational trophoblastic neoplasia: brazilian multicenter retrospective cohort study. [PDF]
Souza LCS +9 more
europepmc +1 more source

