Results 191 to 200 of about 10,583 (250)

AARS2‐SIRT5‐Driven DLD K445 Lactylation Promotes Cuproptosis Resistance in Glioblastoma Stem Cells

open access: yesAdvanced Science, EarlyView.
Lactylation of DLD at K445 by AARS2 suppresses PDH complex activity and reduces DLAT lipoylation, thereby conferring cuproptosis resistance in glioblastoma stem cells. SIRT5‐mediated delactylation restores PDH function and enhances cuproptosis sensitivity.
Mingtian Ding   +12 more
wiley   +1 more source

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

open access: yesAdvanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu   +9 more
wiley   +1 more source

Suppressing Photothermal Artifacts in Flexible Fluorescent Fiber‐Optic Sensors for Accurate and Precise In Situ Temperature Monitoring

open access: yesAdvanced Science, EarlyView.
A partial‐inner‐cladding optical fiber (PICOF) is developed to suppress photothermal artifacts in fluorescent fiber‐optic thermometry by isolating the sensing layer from regions prone to photothermal effects. This structural design strategy enables high‐fidelity operation at elevated excitation power, achieving high accuracy (maximum absolute error ...
Sijie Su   +7 more
wiley   +1 more source

Living Newborn Back-To-Back With a Complete Hydatidiform Mole: A Rare Twin Pregnancy Outcome. [PDF]

open access: yesCase Rep Obstet Gynecol
Abou Chakra R   +5 more
europepmc   +1 more source

SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition

open access: yesAdvanced Science, EarlyView.
The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang   +9 more
wiley   +1 more source

Impact of different EMA/CO treatment regimens in women with gestational trophoblastic neoplasia: brazilian multicenter retrospective cohort study. [PDF]

open access: yesRev Bras Ginecol Obstet
Souza LCS   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy