Results 111 to 120 of about 16,742 (262)

Precision Mapping of Retinal Disease: Identification of Differential Progression Trajectories via Imaging Phenomics

open access: yesiMetaMed, EarlyView.
Applying single‐cell RNA‐seq techniques to large‐scale clinical phenotypic data enables the discovery of differential disease progression trajectories and the construction of data‐driven progression scores. These can then be integrated into precision medicine studies to investigate the drivers of patient‐specific disease outcomes. ABSTRACT We propose a
Christian Anderson   +11 more
wiley   +1 more source

Microbiome‐mediated plant‐soil feedbacks as a tool for resilient agriculture

open access: yesiMetaOmics, EarlyView.
Translating plant‐soil feedbacks (PSFs) into reliable agricultural management requires shifting from input‐dependent practices toward endogenous, process‐driven crop resilience. To bridge this gap, we propose a predictive framework centered on three strategic interventions: engineering the crop holobiont, diversifying the soil habitat, and deploying ...
Muhammad Asif   +4 more
wiley   +1 more source

Enviromics crosstalk between internal and external plant environments for enhanced adaptation and de novo domestication

open access: yesiMeta, EarlyView.
Climate change demands accelerated plant adaptation and de novo domestication. Yet current enviromics focuses disproportionately on external environments, neglecting internal dynamics—gene expression, metabolic flux, and signal transduction—within predictive envirotyping frameworks.
Lin‐An Zhang   +8 more
wiley   +1 more source

The gut microbiome organ

open access: yesiMeta, EarlyView.
The gut microbiome can be conceptualized as a distributed organ‐like functional system with spatially structured organization, broad biochemical capacity, and continuous bidirectional communication with the host. By transforming dietary, host‐derived, and environmental substrates into bioactive metabolites with endocrine‐like, immunomodulatory, and ...
Yang Bi   +22 more
wiley   +1 more source

Context-dependent integrated stress resistance promotes a global invasive pest. [PDF]

open access: yesInsect Sci, 2022
Tarusikirwa VL   +3 more
europepmc   +1 more source

The plant microbiome: From ecological foundations to precision microbial engineering for sustainable agriculture

open access: yesiMeta, EarlyView.
From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei   +26 more
wiley   +1 more source

Biological control of invasive pests in India

open access: yes, 2021
Neeru Dumra   +3 more
openaire   +1 more source

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