INVASIVE PNEUMOCOCCAL DISEASES IN CHILDREN AGED 1-59 MONTHS IN SICILY, ITALY: IMPORTANCE OF ACTIVE FAMILY PAEDIATRICIAN SURVEILLANCE AND VACCINATION COVERAGE. [PDF]
Purpose: Aim of this study was to analyze pediatric invasive pneumococcal disease rates several years after the implementation of infant pneumococcal vaccination. Methods: The study was carried out in Sicily and involved about 30,000 children, aged 1-
Emanuele Amodio
doaj +4 more sources
Mathematical modelling long-term effects of replacing Prevnar7 with Prevnar13 on invasive pneumococcal diseases in England and Wales. [PDF]
England and Wales recently replaced the 7-valent pneumococcal conjugate vaccine (PCV7) with its 13-valent equivalent (PCV13), partly based on projections from mathematical models of the long-term impact of such a switch compared to ceasing pneumococcal ...
Yoon Hong Choi +4 more
doaj +5 more sources
Invasive pneumococcal disease presenting with abdominal pain, vomiting and diarrhoea in a patient with multiple myeloma [PDF]
Background: Streptococcus pneumoniae is a leading cause of community-acquired pneumonia and meningitis, but intra-abdominal manifestations are rare, particularly in adults without underlying peritoneal disease.
Hélder Diogo Gonçalves +6 more
doaj +2 more sources
Minimum incidence of adult invasive pneumococcal disease in Blantyre, Malawi an urban african setting: a hospital based prospective cohort study. [PDF]
Invasive pneumococcal disease causes substantial morbidity and mortality in Africa. Evaluating population level indirect impact on adult disease of pneumococcal conjugate vaccine (PCV) programmes in infants requires baseline population incidence rates ...
Naor Bar-Zeev +4 more
doaj +5 more sources
Outbreak of Serotype 1 Invasive Pneumococcal Disease, Kibera Urban Informal Settlement, Nairobi, Kenya, 2023 [PDF]
Use of 10-valent pneumococcal conjugate vaccine in Kenya has led to substantial reductions in vaccine-type pneumococcal carriage and invasive pneumococcal disease.
Terry Komo +20 more
doaj +2 more sources
Pneumococcal carriage in sub-Saharan Africa--a systematic review. [PDF]
BACKGROUND: Pneumococcal epidemiology varies geographically and few data are available from the African continent. We assess pneumococcal carriage from studies conducted in sub-Saharan Africa (sSA) before and after the pneumococcal conjugate vaccine (PCV)
A Fenoll +91 more
core +29 more sources
Pneumococcal serotypes and their association with death risk in invasive pneumococcal disease: a systematic review and meta-analysis [PDF]
BackgroundStreptococcus pneumoniae and its infections are a global public health concern. Invasive pneumococcal disease accounts for significant mortality in the aged and immunocompromised. Over 100 unique capsular serotypes have been identified, with 80–
Samuel Darkwah +3 more
doaj +2 more sources
Despite advances in preventative interventions, invasive pneumococcal disease and pneumonia cause significant morbidity and mortality in children. We studied the annual incidence of pneumococcal-specific and syndromic invasive disease and non-invasive ...
Elisa Barbieri +9 more
doaj +1 more source
Invasive pneumococcal disease [PDF]
Streptococcus pneumoniae , the pneumococcus, is a Gram-positive diplococcus with more than 90 serotypes determined by the polysaccharide composition of its capsule. It is carried asymptomatically in approximately 50% of people.1 It can cause both non-invasive and invasive disease.
Elise, Randle +2 more
openaire +2 more sources
Cardiotoxicity during Invasive Pneumococcal Disease [PDF]
Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and sepsis, with adult hospitalization linked to approximately 19% incidence of an adverse cardiac event (e.g., heart failure, arrhythmia, infarction). Herein, we review the specific host-pathogen interactions that contribute to cardiac dysfunction during invasive ...
Brown, AO +3 more
openaire +4 more sources

