Mathematical modelling long-term effects of replacing Prevnar7 with Prevnar13 on invasive pneumococcal diseases in England and Wales. [PDF]
England and Wales recently replaced the 7-valent pneumococcal conjugate vaccine (PCV7) with its 13-valent equivalent (PCV13), partly based on projections from mathematical models of the long-term impact of such a switch compared to ceasing pneumococcal ...
Yoon Hong Choi+4 more
doaj +28 more sources
Indirect effects of childhood pneumococcal conjugate vaccination on invasive pneumococcal disease: a systematic review and meta-analysis [PDF]
Summary: Background: The full extent to which childhood pneumococcal conjugate vaccines (PCV) can indirectly reduce illness in unvaccinated populations is not known.
Tinevimbo Shiri, DrPhD+7 more
doaj +5 more sources
Risk factors associated with mortality in invasive pneumococcal disease remain unclear. The present work is a meta-analysis of studies that enrolled only patients with invasive pneumococcal disease and reported on mortality.
Hao Chen+5 more
doaj +2 more sources
INVASIVE PNEUMOCOCCAL DISEASES IN CHILDREN AGED 1-59 MONTHS IN SICILY, ITALY: IMPORTANCE OF ACTIVE FAMILY PAEDIATRICIAN SURVEILLANCE AND VACCINATION COVERAGE. [PDF]
Purpose: Aim of this study was to analyze pediatric invasive pneumococcal disease rates several years after the implementation of infant pneumococcal vaccination. Methods: The study was carried out in Sicily and involved about 30,000 children, aged 1-
Emanuele Amodio
doaj +4 more sources
Sustained Reductions in Invasive Pneumococcal Disease in the Era of Conjugate Vaccine [PDF]
BACKGROUND Changes in invasive pneumococcal disease (IPD) incidence were evaluated after 7 years of 7-valent pneumococcal conjugate vaccine (PCV7) use in US children.
Tamara Pilishvili+13 more
openalex +2 more sources
Optimising assessments of the epidemiological impact in The Netherlands of paediatric immunisation with 13-valent pneumococcal conjugate vaccine using dynamic transmission modelling. [PDF]
This work is the first attempt to quantify the overall effects of a 13-valent pneumococcal conjugate vaccine (PCV13) vaccination programme in the Dutch population taking into account all the direct and indirect effects of the vaccine on invasive ...
Elisabetta De Cao+3 more
doaj +7 more sources
BackgroundDespite the widespread implementation of the pneumococcal conjugate vaccine, Streptococcus pneumoniae remains the leading cause of severe pneumonia associated with mortality among children less than 5 years of age worldwide, with the highest ...
James Samwel Ngocho+6 more
doaj +2 more sources
Minimum incidence of adult invasive pneumococcal disease in Blantyre, Malawi an urban african setting: a hospital based prospective cohort study. [PDF]
Invasive pneumococcal disease causes substantial morbidity and mortality in Africa. Evaluating population level indirect impact on adult disease of pneumococcal conjugate vaccine (PCV) programmes in infants requires baseline population incidence rates ...
Naor Bar-Zeev+4 more
doaj +3 more sources
Key Points Question Was the implementation of nonpharmaceutical interventions (NPIs) during the COVID-19 pandemic associated with changes in the incidence of invasive pneumococcal disease (IPD) and associated pneumococcal carriage and respiratory viral ...
A. Rybak+18 more
semanticscholar +1 more source
Despite advances in preventative interventions, invasive pneumococcal disease and pneumonia cause significant morbidity and mortality in children. We studied the annual incidence of pneumococcal-specific and syndromic invasive disease and non-invasive ...
Elisa Barbieri+9 more
doaj +1 more source