Burden of Invasive Pneumococcal Disease
TO THE EDITOR—We read with interest the article by Kent et al [1]. The authors note that the burden of invasive pneumococcal disease (IPD) in UK infants aged
Slack, Mary +6 more
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Immunodeficiency in Children With Invasive Pneumococcal Disease. [PDF]
Invasive pneumococcal disease (IPD) continues to be a significant contributor to childhood morbidity and mortality. Such occurrences persist despite global vaccination initiatives. Previously unrecognized immunodeficiencies are highlighted due to the presence of IPD in otherwise healthy children.
Almesfer AM +3 more
europepmc +3 more sources
Anticipating impact of implementing PCV20 or PCV21 vaccines for older adults in the immunisation programme for invasive pneumococcal disease, using nationwide surveillance data, Israel, 2009 to 2024 [PDF]
BACKGROUND Pneumococcal conjugate vaccines (PCVs) have reduced vaccine-type (VT) invasive pneumococcal disease (IPD) in older adults through direct and indirect effects. However, non-vaccine-type serotypes have emerged.
on behalf of the Israeli Adult Pneumococcal Invasive Disease (IAIPD) group
doaj +2 more sources
Invasive pneumococcal disease presenting with abdominal pain, vomiting and diarrhoea in a patient with multiple myeloma [PDF]
Background: Streptococcus pneumoniae is a leading cause of community-acquired pneumonia and meningitis, but intra-abdominal manifestations are rare, particularly in adults without underlying peritoneal disease.
Hélder Diogo Gonçalves +6 more
doaj +2 more sources
Mathematical modelling long-term effects of replacing Prevnar7 with Prevnar13 on invasive pneumococcal diseases in England and Wales. [PDF]
IntroductionEngland and Wales recently replaced the 7-valent pneumococcal conjugate vaccine (PCV7) with its 13-valent equivalent (PCV13), partly based on projections from mathematical models of the long-term impact of such a switch compared to ceasing ...
Yoon Hong Choi +4 more
doaj +5 more sources
Effect of pneumococcal conjugate vaccination on serotype-specific carriage and invasive disease in England: a cross-sectional study [PDF]
We investigated the effect of the 7-valent pneumococcal conjugate vaccine (PCV7) programme in England on serotype-specific carriage and invasive disease to help understand its role in serotype replacement and predict the impact of higher valency vaccines.
Flasche, Stefan +7 more
core +5 more sources
BackgroundStreptococcus pneumoniae and its infections are a global public health concern. Invasive pneumococcal disease accounts for significant mortality in the aged and immunocompromised. Over 100 unique capsular serotypes have been identified, with 80–
Samuel Darkwah +3 more
doaj +3 more sources
Despite advances in preventative interventions, invasive pneumococcal disease and pneumonia cause significant morbidity and mortality in children. We studied the annual incidence of pneumococcal-specific and syndromic invasive disease and non-invasive ...
Elisa Barbieri +9 more
doaj +1 more source
Invasive pneumococcal disease [PDF]
Streptococcus pneumoniae , the pneumococcus, is a Gram-positive diplococcus with more than 90 serotypes determined by the polysaccharide composition of its capsule. It is carried asymptomatically in approximately 50% of people.1 It can cause both non-invasive and invasive disease.
Elise, Randle +2 more
openaire +2 more sources
Invasive pneumococcal disease in Greenland [PDF]
The Inuit of Alaska and Canada have a higher incidence of invasive pneumococcal disease than non-inuit. The purpose of the present study was to evaluate incidence and outcome of these infections in Greenland with special reference to pneumococcal serotypes.Retrospective study of invasive pneumococcal infections in Greenland in the period 1996-2002 ...
J, Christiansen +2 more
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