Results 91 to 100 of about 355,625 (242)

Novel clones of Streptococcus pneumoniae causing invasive disease in Malaysia. [PDF]

PLoS ONE, 2014
Although Streptococcus pneumoniae is a leading cause of childhood disease in South East Asia, little has previously been reported regarding the epidemiology of invasive pneumococcal disease in Malaysia and very few studies have explored pneumococcal ...
Johanna M Jefferies, Mohd Yasim Mohd Yusof, Shamala Devi Sekaran, Stuart C Clarke   +3 more
doaj   +1 more source

Evaluation of differences in S. pneumoniae colonization among children with and without clinically diagnosed asthma/wheeze [PDF]

, 2017
Streptococcus pneumoniae colonization is the nasopharynx is common in young children. Colonization of S. pneumoniae is a necessary precursor for invasive pneumococcal disease (IPD), which is a major cause of morbidity and mortality among children less ...
Alishahi, Musheng
core  

Nasopharyngeal S. pneumoniae carriage and density in Belgian infants after 9 years of pneumococcal conjugate vaccine programme [PDF]

, 2018
Background: In Belgium, the infant pneumococcal conjugate vaccine (PCV) programme changed from PCV7 (2007-2011) to PCV13 (2011-2015) and to PCV10 (2015-2016). A 3-year nasopharyngeal carriage study was initiated during the programme switch in 2016.
Blaizot, Stéphanie, Desmet, Stefanie, Goossens, Herman, Malhotra-Kumar, Surbhi, NPcarriage study group, the, Theeten, Heidi, Van Damme, Pierre, Van Heirstraeten, Liesbet, Van Herck, Koen, Verhaegen, Jan, Wouters, Ine   +10 more
core   +2 more sources

Effects of PCV7 and PCV13 on invasive pneumococcal disease and carriage in Stockholm, Sweden

European Respiratory Journal, 2016
The effects of pneumococcal conjugated vaccines (PCVs) need to be investigated. In Stockholm County, Sweden, PCV7 was introduced in the childhood immunisation programme in 2007 and changed to PCV13 in 2010.
I. Galanis, A. Lindstrand, J. Darenberg, Sarah Browall, Priyanka Nannapaneni, Karin Sjöström, E. Morfeldt, P. Nauclér, M. Blennow, Å. Örtqvist, B. Henriques-Normark   +10 more
semanticscholar   +1 more source

Targeted Therapies for Rheumatoid Arthritis in Super‐Elderly Society: Insights From FIRST Registry, Japan

International Journal of Rheumatic Diseases, Volume 28, Issue 4, April 2025.
ABSTRACT As the world's most rapidly aging society, Japan has faced significant challenges in the management of rheumatoid arthritis (RA) in elderly patients. Biologic and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) have improved disease control, but concerns remain regarding the risk of infection and malignancy, especially in
Koshiro Sonomoto, Yoshiya Tanaka
wiley   +1 more source

Genetic Variation in NFKBIE Is Associated With Increased Risk of Pneumococcal Meningitis in Children

EBioMedicine, 2016
Background: Streptococcus pneumoniae and Neisseria meningitidis are frequent pathogens in life-threatening infections. Genetic variation in the immune system may predispose to these infections.
Lene F. Lundbo, Zitta Barrella Harboe, Louise N. Clausen, Mads V. Hollegaard, Henrik T. Sørensen, David M. Hougaard, Helle B. Konradsen, Mette Nørgaard, Thomas Benfield   +8 more
doaj   +1 more source

Prevalence and clonal distribution of pcpA, psrP and Pilus-1 among pediatric isolates of Streptococcus pneumoniae. [PDF]

PLoS ONE, 2012
Streptococcus pneumoniae is the leading cause of vaccine-preventable deaths globally. The objective of this study was to determine the distribution and clonal type variability of three potential vaccine antigens: Pneumococcal serine-rich repeat protein ...
Laura Selva, Pilar Ciruela, Krystle Blanchette, Eva del Amo, Roman Pallares, Carlos J Orihuela, Carmen Muñoz-Almagro   +6 more
doaj   +1 more source

Suppressing epidemic spreading in multiplex networks with social-support [PDF]

, 2017
Although suppressing the spread of a disease is usually achieved by investing in public resources, in the real world only a small percentage of the population have access to government assistance when there is an outbreak, and most must rely on resources from family or friends.
arxiv   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2024: A year in review

British Journal of Pharmacology, Volume 182, Issue 7, Page 1416-1445, April 2025.
Abstract In the past year, the European Medicines Agency (EMA), the Food and Drug Administration (FDA) and the Medicines and Healthcare Products Regulatory Agency (MHRA) authorised 53 novel drugs. While the 2024 harvest is not as rich as in 2023, when 70 new chemical entities were approved, the number of ‘orphan’ drug authorisations in 2024 (21) is ...
Stavros Topouzis, Andreas Papapetropoulos, Steve P. H. Alexander, Miriam Cortese‐Krott, Dave A. Kendall, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Mauro M. Teixeira, Nathalie Vergnolle, Xin Wang, Péter Ferdinandy   +16 more
wiley   +1 more source

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitis [PDF]

, 2019
Streptococcus pneumoniae is a common nasopharyngeal colonizer, but can also cause life-threatening invasive diseases such as empyema, bacteremia and meningitis.
Barrett, J, Benfield, T, Bentley, S, Bootsma, H, Brouwer, M, Croucher, N, De Groot, LCPGM, Du Plessis, M, Ferwerda, B, Gladstone, R, Harboe, Z, Knight, JC, Kremer, PHC, Lees, J, Lundbo, L, Madhi, S, Mentzer, Alexander, Mills, T, Nohr, E, Nzenze, S, Parkhill, J, Rots, N, Sanders, EAM, Sørensen, TIA, Trzciński, K, Valls Serón, M Valls, Van De Beek, D, Van Den Berg, L, Van Der Ende, A, Van Der Velde, N, Van Rheenen, W, Van Schoor, N, Veldink, J, Von Gottberg, A, Weiser, J, Wheeler, N, Wijmega-Monsuur, A, Wyllie, A, Zwinderman, A, Ängquist, L   +39 more
core   +7 more sources