Results 91 to 100 of about 38,448 (217)

The ZNF148‐ZEB1‐AS1‐IGF2BP2‐NOD2 Axis Drives Microglial Antipneumococcal Immunity in Bacterial Meningitis

Glia, Volume 74, Issue 2, February 2026.
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Xiufu Hu, Fang Jiang, Xinjie Liu, Ling Li, Ruimei Hu, Meng Dong, Aihua Cao   +6 more
wiley   +1 more source

Isolation site influences virulence phenotype of serotype 14 Streptococcus pneumoniae strains belonging to multilocus sequence type 15 [PDF]

, 2015
Streptococcus pneumoniae is a diverse species causing invasive as well as localized infections that result in massive global morbidity and mortality. Strains vary markedly in pathogenic potential, but the molecular basis is obscured by the diversity and ...
Amin, Zarina, Harvey, Richard M., Hughes, Catherine E., Paton, Adrienne W., Paton, James C., Trappetti, Claudia, Wang, Hui   +6 more
core   +1 more source

Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection [PDF]

, 2013
Streptococcus pneumoniae of serotype 3 possess a mucoid capsule and cause disease associated with high mortality rates relative to other pneumococci. Phylogenetic analysis of a complete reference genome and 81 draft sequences from clonal complex 180, the
Barquist, L, Bentley, SD, Browall, S, Croucher, NJ, Dordel, J, Feltwell, T, Fookes, MC, Gould, KA, Harris, SR, Henriques-Normark, B, Hinds, J, Inverarity, D, Mitchell, AM, Mitchell, TJ, Normark, S, Parkhill, J, Salter, SJ, Zemlickova, H   +17 more
core   +4 more sources

Risk for Invasive Streptococcal Infections among Adults Experiencing Homelessness, Anchorage, Alaska, USA, 2002–2015

Emerging Infectious Diseases, 2019
The risk for invasive streptococcal infection has not been clearly quantified among persons experiencing homelessness (PEH). We compared the incidence of detected cases of invasive group A Streptococcus infection, group B Streptococcus infection, and ...
Emily Mosites, Tammy Zulz, Dana Bruden, Leisha Nolen, Anna Frick, Louisa Castrodale, Joseph McLaughlin, Chris Van Beneden, Thomas W. Hennessy, Michael G. Bruce   +9 more
doaj   +1 more source

Variation at the capsule locus, cps, of mistyped and non-typable Streptococcus pneumoniae isolates [PDF]

, 2012
The capsule polysaccharide locus (cps) is the site of the capsule biosynthesis gene cluster in encapsulated Streptococcus pneumoniae. A set of pneumococcal samples and non-pneumococcal streptococci from Denmark, the Gambia, the Netherlands, Thailand, the
Antonio, M, Bentley, SD, Bootsma, HJ, Gould, KA, Hanage, WP, Hermans, PW, Hinds, J, Lambertsen, L, O'Brien, KL, Salter, SJ, Turner, P   +10 more
core   +1 more source

Kawasaki Disease and Invasive Pneumococcal Infection [PDF]

SN Comprehensive Clinical Medicine, 2020
Emi Kijima, Haruka Yamamura, Mari Okada, Masayuki Nagasawa   +3 more
openaire   +2 more sources

Evolution of antimicrobial resistance and serotype distribution of Streptococcus pneumoniae isolated from children with invasive and noninvasive pneumococcal diseases in Algeria from 2005 to 2012

New Microbes and New Infections, 2015
Pneumococcal infections are a major cause of morbidity and mortality in developing countries. The introduction of pneumococcal conjugate vaccines (PCVs) has dramatically reduced the incidence of pneumococcal diseases. PCVs are not currently being used in
N. Ramdani-Bouguessa, H. Ziane, S. Bekhoucha, Z. Guechi, A. Azzam, D. Touati, M. Naim, S. Azrou, M. Hamidi, A. Mertani, A. Laraba, T. Annane, S. Kermani, M. Tazir   +13 more
doaj   +1 more source

Non-vaccine Pneumococcal Serotypes Among Children with Invasive Pneumococcal Disease

Indian Pediatrics, 2018
To report the percentage of non-vaccine pneumococcal serotypes and their antibiotic susceptibility pattern in children with invasive peumococcal disease.Invasive pneumococcal isolates of children
James, John, Rosemol, Varghese, Jones, Lionell, Ayyanraj, Neeravi, Balaji, Veeraraghavan   +4 more
openaire   +2 more sources

Pre‐Transplant Infection Screening and Vaccination During Prolonged Waiting Periods for Lung Transplantation in Donor‐Limited Asia‐Pacific Settings

Respirology, Volume 31, Issue 3, Page 232-235, March 2026.
Takashi Hirama, Miki Nagao, Yoshinori Okada   +2 more
wiley   +1 more source

Herd effects of child vaccination with pneumococcal conjugate vaccine against pneumococcal non-invasive community-acquired pneumonia: What is the evidence?

Human Vaccines & Immunotherapeutics, 2017
Quantification of pneumococcal conjugate vaccines (PCVs) herd effects are mainly performed on invasive pneumococcal disease (IPD) but there is conflicting evidence regarding herd effects of PCVs on non-IPD pneumococcal community-acquired pneumonia.
Cornelis H. van Werkhoven
doaj   +1 more source