BackgroundCurrent diagnostic methods for detection of Streptococcus pneumoniae in children with suspected invasive pneumococcal disease have limitations of accuracy, timeliness, and patient convenience.
Pedro Brotons+11 more
doaj +1 more source
Challenges in estimating the impact of pneumococcal conjugate vaccines through surveillance [PDF]
SCOPUS: re.jinfo:eu-repo/semantics ...
Hanquet, Germaine, Vergison, Anne
core +1 more source
Non-invasive modelling methodology for the diagnosis of Coronary Artery Disease using Fuzzy Cognitive Maps [PDF]
Cardiovascular Diseases (CVD) and strokes produce immense health and economic burdens globally. Coronary Artery Disease (CAD) is the most common type of cardiovascular disease. Coronary Angiography, which is an invasive treatment, is also the standard procedure for diagnosing CAD.
arxiv +1 more source
Rare but not forgotten: A case of meningitis due to ceftriaxone-resistant Streptococcus pneumoniae
Despite the dramatic decrease in invasive pneumococcal disease since the widespread use of the first pneumococcal vaccine, invasive and resistant disease still occurs.
Naomi Hauser+3 more
doaj +1 more source
IL-17 can be protective or deleterious in murine pneumococcal pneumonia [PDF]
Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection.
Bayes, Hannah K.+4 more
core +3 more sources
An Exact Relationship Between Invasion Probability and Endemic Prevalence for Markovian SIS Dynamics on Networks [PDF]
Understanding models which represent the invasion of network-based systems by infectious agents can give important insights into many real-world situations, including the prevention and control of infectious diseases and computer viruses. Here we consider Markovian susceptible-infectious-susceptible (SIS) dynamics on finite strongly connected networks,
arxiv +1 more source
From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]
In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core +3 more sources
Hierarchical Classification of Pulmonary Lesions: A Large-Scale Radio-Pathomics Study [PDF]
Diagnosis of pulmonary lesions from computed tomography (CT) is important but challenging for clinical decision making in lung cancer related diseases. Deep learning has achieved great success in computer aided diagnosis (CADx) area for lung cancer, whereas it suffers from label ambiguity due to the difficulty in the radiological diagnosis. Considering
arxiv +1 more source
Population-based estimates of the effectiveness of pneumococcal vaccination in Australia
Objectives Australia’s Childhood Immunisation Register (ACIR) is one of only a handful of national immunisation registers world-wide. We have, for the first time, linked the ACIR to other health datasets to measure the real-world impact of Australia’s ...
Heather Gidding+6 more
doaj +1 more source
Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types [PDF]
We describe associations between death from invasive pneumococcal disease (IPD) and particular serogroups and sequence types (STs) determined by multilocus sequence typing (MLST) using data from Scotland.
Andrew Smith+24 more
core +3 more sources