Results 41 to 50 of about 38,448 (217)

Potential impact of replacing the 13-valent pneumococcal conjugate vaccine with 15-valent or 20-valent pneumococcal conjugate vaccine in the 1 + 1 infant schedule in England: a modelling study

The Lancet Public Health
Summary: Background: Paediatric pneumococcal conjugate vaccine (PCV) programmes in England using seven-valent PCV (PCV7) in 2006 and 13-valent PCV (PCV13) in 2010 have reduced vaccine-type invasive pneumococcal disease, but the overall effect has been ...
Yoon Hong Choi, PhD, Marta Bertran, MSc, David J Litt, PhD, Shamez N Ladhani, ProfPhD, Elizabeth Miller, ProfFMedSci   +4 more
doaj   +1 more source

Effectiveness of pneumococcal conjugate vaccines against invasive pneumococcal disease among children under five years of age in Africa: A systematic review.

PLoS ONE, 2019
BackgroundDespite the widespread implementation of the pneumococcal conjugate vaccine, Streptococcus pneumoniae remains the leading cause of severe pneumonia associated with mortality among children less than 5 years of age worldwide, with the highest ...
James Samwel Ngocho, Best Magoma, Gaudencia Alois Olomi, Michael Johnson Mahande, Sia Emmanueli Msuya, Marien Isaäk de Jonge, Blandina Theophil Mmbaga   +6 more
doaj   +1 more source

Genetic susceptibility to invasive pneumococcal disease

Infection, Genetics and Evolution, 2018
The pathogenesis of IPD remains unknown, especially among middle-aged individuals without risk factors (WRF).The aim of the present study was to investigate the role of single nucleotide polymorphisms (SNP) within key genes involved in innate immune response on IPD susceptibility.Forty-three SNPs within 10 immunological genes were investigated in a ...
Anna, Sangil, María J, Arranz, Roberto, Güerri-Fernández, Maite, Pérez, Helena, Monzón, Antoni, Payeras, Marta, Andrés, Jorge, Torviso, Laura, Ibañez, Javier, Garau, Esther, Calbo   +10 more
openaire   +2 more sources

Preventive measures in infancy to reduce under-five mortality: a case-control study in The Gambia.

, 2009
OBJECTIVE: To investigate the relationship between child mortality and common preventive interventions: vaccination, trained birthing attendants, tetanus toxoid during pregnancy, breastfeeding and vitamin A supplementation. METHODS: Case-control study in
Adegbola, Richard A, Dockerty, John D, Herbison, Peter, Hill, Philip C, Howie, Stephen RC, Jasseh, Momodou, Jeffries, David J, Mulholland, Kim, Rutherford, Merrin E   +8 more
core   +1 more source

Preventing Invasive Pneumococcal Disease in Children [PDF]

The Journal of the American Board of Family Medicine, 2003
Streptococcus pneumoniae is a major bacterial cause of sepsis, meningitis, and otitis media in infants and young children. In 1999, the Active Bacterial Core Surveillance Network reported a rate of invasive pneumococcal disease of 165.7 per 100,000 in children younger than 1 year old and a rate ...
openaire   +2 more sources

A population-based study on the burden of hospitalized pediatric pneumococcal disease in Taiwan before and after the introduction of 13-valent pneumococcal conjugate vaccine into the childhood immunization program in 2015

BMC Infectious Diseases
Background To estimate the burden of invasive pneumococcal disease, non-bacteremic pneumococcal pneumonia, and acute otitis media before and after inclusion of the 13-valent pneumococcal vaccine (PCV13) into Taiwan’s Childhood Immunization Program in ...
Ting-An Yen, Jhong-Lin Wu, Chi-Chuan Wang, Ling-Ya Huang, See-Hwee Yeo, Dony Patel, Cindy Thiow Koon Lim, Hung-Wei Lin, Eriko Yamada, Isaya Sukarom   +9 more
doaj   +1 more source

Nasopharyngeal carriage rate of Streptococcus pneumoniae in Ugandan children with Sickle Cell Disease [PDF]

, 2012
BackgroundNasopharyngeal carriage ofStreptococcus pneumoniaeis a determinant for invasive pneumococcal disease, which often complicates homozygous sickle cell disease. Here, we determined the nasopharyngeal carriage rate ofS.
David P Kateete, Henry Kajumbula, Deogratias H Kaddu-Mulindwa, Augustine K Ssevviri   +3 more
core   +2 more sources

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

Spontaneous pneumococcal peritonitis diagnosed by qPCR

IDCases, 2019
Spontaneous bacterial peritonitis is an uncommon manifestation of invasive pneumococcal disease and frequently occurs when an underlying hepatic disease is present. Bacterial identification through culture can be particularly challenging in patients with
Daniel Jarovsky, Thais Grodzicki Ambrus, Mariana Galvão Gurgel, Marcelo Jenné Mimica, Mariana Volpe Arnoni, Flávia Jacqueline Almeida, Marco Aurélio Palazzi Sáfadi, Eitan Naaman Berezin   +7 more
doaj   +1 more source

Pneumococcal serotypes in children in 4 European countries [PDF]

, 2010
After heptavalent pneumococcal conjugate vaccine (PCV7) was marketed in France, Spain, Belgium, and England and Wales (United Kingdom), invasive disease from non-PCV7 serotypes (NVT) increased. Adjusted serotype-specific incidences among children
Fenoll, Asuncion, George, Robert, Hanquet, Germaine, Kissling, Esther, Lepoutre, Agnes, Lernout, Tinne, Tarrago, David, Varon, Emmanuelle, Verhaegen, Jan   +8 more
core   +3 more sources