Seasonality and outbreak of a predominant Streptococcus pneumoniae serotype 1 clone from The Gambia: expansion of ST217 hypervirulent clonal complex in West Africa. [PDF]
, 2008 BACKGROUND: Streptococcus pneumoniae serotype 1 causes > 20% of invasive disease, among all age groups combined, in The Gambia. In contrast, it is rarely detected in carriage studies. This study compares the molecular epidemiology of S.
Adegbola, Richard A +15 more
core +2 more sources
The interactions of SARS-CoV-2 with co-circulating pathogens: Epidemiological implications and current knowledge gaps [PDF]
arXiv, 2022 Despite the availability of effective vaccines, the persistence of SARS-CoV-2 suggests that co-circulation with other pathogens and resulting multi-epidemics may become increasingly frequent. To better forecast and control the risk of such multi-epidemics, it is essential to elucidate the potential interactions of SARS-CoV-2 with other pathogens; these
arxiv
Haptic Simulator for Liver Diagnostics through Palpation [PDF]
Medicine Meets Virtual Reality 19, 2012, pp.156-160, 2019 Mechanical properties of biological tissue for both histological and pathological considerations are often required in disease diagnostics. Such properties can be simulated and explored with haptic technology. Development of cost effective haptic-based simulators and their introduction in the minimally invasive surgery learning cycle is still in its ...
arxiv +1 more source
Development of primary invasive pneumococcal disease caused by serotype 1 pneumococci is driven by early increased type I interferon response in the lung [PDF]
, 2014 The pneumococcus is the world's foremost respiratory pathogen, but the mechanisms allowing this pathogen to proceed from initial asymptomatic colonization to invasive disease are poorly understood.
Harvey, Richard M. +3 more
core +1 more source
Molecular epidemiology of pneumococci obtained from Gambian children aged 2-29 months with invasive pneumococcal disease during a trial of a 9-valent pneumococcal conjugate vaccine. [PDF]
, 2008 BACKGROUND: The study describes the molecular epidemiology of Streptococcus pneumoniae causing invasive disease in Gambian children METHODS: One hundred and thirty-two S. pneumoniae isolates were recovered from children aged 2-29 months during the course
Adegbola, Richard A +14 more
core +2 more sources
Predicting invasive ductal carcinoma using a Reinforcement Sample Learning Strategy using Deep Learning [PDF]
arXiv, 2021 Invasive ductal carcinoma is a prevalent, potentially deadly disease associated with a high rate of morbidity and mortality. Its malignancy is the second leading cause of death from cancer in women. The mammogram is an extremely useful resource for mass detection and invasive ductal carcinoma diagnosis.
arxiv
PLoS ONE, 2019 Background Ontario, Canada introduced a publicly-funded 13-valent pneumococcal conjugate vaccine (PCV13) for infants in 2010, replacing the 10-valent (PCV10, 2009–2010) and the 7-valent (PCV7, 2005–2009) conjugate vaccine programs; a 23-valent ...
S. Wijayasri +5 more
semanticscholar +1 more source
Emerging Infectious DiseasesUse of 10-valent pneumococcal conjugate vaccine in Kenya has led to substantial reductions in vaccine-type pneumococcal carriage and invasive pneumococcal disease.
Terry Komo +20 more
doaj +1 more source
Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection [PDF]
, 2004 Streptococcus pneumoniae is an important human pathogen responsible for high mortality and morbidity worldwide. The susceptibility to pneumococcal infections is controlled by as yet unknown genetic factors.
Jonczyk, Magda S. +7 more
core +5 more sources
Effect of high-valency pneumococcal conjugate vaccines on invasive pneumococcal disease in children in SpIDnet countries: an observational multicentre study [PDF]
, 2017 Background The Streptococcus pneumoniae Invasive Disease network (SpIDnet) actively monitors populations in nine sites in seven European countries for invasive pneumococcal disease.
Castilla, Jesus +20 more
core +1 more source